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HFCAS OpenIR

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Novel HIVEP1-ALK fusion in a patient with lung adenocarcinoma demonstrating sensitivity to alectinib: a case report 期刊论文
TRANSLATIONAL LUNG CANCER RESEARCH, 2022, 卷号: 11
作者:  Gu, Xiaodong;  Wang, Wenxian;  Wu, Wei;  Zhang, Yiping;  Shao, Lan;  Santarpia, Mariacarmela;  Christopoulos, Petros;  Myall, Nathaniel J.;  Shi, Zhiyong;  Lou, Guangyuan
收藏  |  浏览/下载：33/0  |  提交时间：2022/12/22
Non-small cell lung cancer (NSCLC)  HIVEP1-ALK  alectinib  intergenic region (IGR)  case report  
Discovery of N-(5-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-4-methoxy-2-(4-methyl-1,4-diazepan-1-yl)phenyl)acrylamide (CHMFL-ALK/EGFR-050) as a potent ALK/EGFR dual kinase inhibitor capable of overcoming a variety of ALK/EGFR associated drug resistant mutants in NSCLC 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 139, 期号: 无, 页码: 674-697
作者:  Chen, Yongfei;  Wu, Jiaxin;  Wang, Aoli;  Qi, Ziping;  Jiang, Taoshan;  Chen, Cheng;  Zou, Fengming;  Hu, Chen;  Wang, Wei;  Wu, Hong;  Hu, Zhenquan;  Wang, Wenchao;  Wang, Beilei;  Wang, Li;  Ren, Tao;  Zhang, Shanchun;  Liu, Qingsong;  Liu, Jing
浏览  |  Adobe PDF(12656Kb)  |  收藏  |  浏览/下载：21275/11466  |  提交时间：2018/08/17
Egfr  Alk  Dual Kinase Inhibitor  Non-small Cell Lung Cancer  
JQ1 synergizes with the Bcl-2 inhibitor ABT-263 against MYCN-amplified small cell lung cancer 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 49, 页码: 86312-86324
作者:  Wang, Huogang;  Hong, Bo;  Li, Xuemin;  Deng, Ke;  Li, Hong;  Lui, Vivian Wai Yan;  Lin, Wenchu
浏览  |  Adobe PDF(9738Kb)  |  收藏  |  浏览/下载：92/39  |  提交时间：2018/08/17
Small Cell Lung Cancer  N-myc  Bcl-2  Jq1  Abt-263