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中国科学院合肥物质科学研究院机构知识库
Knowledge Management System of Hefei Institute of Physical Science,CAS
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Aberrant copper metabolism and hepatic inflammation cause neurological manifestations in a mouse model of Wilson's disease
期刊论文
JOURNAL OF NEUROINFLAMMATION, 2024, 卷号: 21
Authors:
Dong, Jianjian
;
Xiang, Guanghai
;
Xia, Xiaoxue
;
Xu, Lewen
;
Wen, Peihua
;
Xu, Chenchen
;
Xu, Yin
;
Su, Yushuang
;
Song, Yanze
;
Tong, Haiyang
;
Zhu, Qingjun
;
Han, Yongzhu
;
Han, Yongsheng
;
Cheng, Nan
;
Wang, Haoyi
;
Zhou, Hong
Favorite
  |  
View/Download:2/0
  |  
Submit date:2024/11/20
Wilson's disease
ATP7B gene
R778L point mutation
Hepatic inflammation
Neurological manifestations
CRISPR/Cas9
A novel PDGFR inhibitor WQ-C-401 prevents pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension
期刊论文
EXPERIMENTAL CELL RESEARCH, 2024, 卷号: 441
Authors:
Huang, Wen
;
Zhou, Hong
;
He, Yiting
;
Wang, Aoli
;
Wang, Beilei
;
Chen, Yongfei
;
Liu, Chenyang
;
Wang, Hong
;
Xie, Weiping
;
Kong, Hui
Favorite
  |  
View/Download:2/0
  |  
Submit date:2024/11/22
WQ-C-401
Pulmonary arterial hypertension
Pulmonary vascular remodeling
Platelet-derived growth factor receptor
Smooth muscle cells
Sevoflurane enhances autophagy via Rac1 to attenuate lung ischaemia-reperfusion injury
期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2024, 卷号: 397
Authors:
Ding, Xian
;
Gao, Xiang
;
Ren, Aolin
;
Xu, Jingjing
;
Jiang, Xuliang
;
Liang, Xiao
;
Xie, Kangjie
;
Zhou, Yan
;
Hu, Chunxiao
;
Huang, Dongxiao
Favorite
  |  
View/Download:1/0
  |  
Submit date:2024/11/20
Lung ischaemia-reperfusion injury
Sevoflurane
Rac1
Autophagy
Daqing formula ameliorated allergic asthma and airway dysbacteriosis in mice challenged with ovalbumin and ampicillin
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 318
Authors:
Wu, Li-ren
;
Peng, Qian-Yu
;
Li, Xue-Jian
;
Guo, Mei-Ying
;
He, Jia-Qi
;
Ying, Hua-Zhong
;
Yu, Chen-Huan
Favorite
  |  
View/Download:39/0
  |  
Submit date:2023/11/10
Lung dysbiosis
Th1/Th2 balance
Antibiotic
GSK-3 ss
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2
期刊论文
EMBO REPORTS, 2022
Authors:
Li, Hui
;
Wang, Ning
;
Jiang, Yu
;
Wang, Haofei
;
Xin, Zengfeng
;
An, Huazhang
;
Pan, Hao
;
Ma, Wangqian
;
Zhang, Ting
;
Wang, Xiaojian
;
Lin, Wenlong
Favorite
  |  
View/Download:45/0
  |  
Submit date:2022/12/22
IL-17R signaling
inflammation
MEKK2
NEDD4L
ubiquitination
3,3 '-Diindolylmethane attenuates inflammation and fibrosis in radiation-induced lung injury by regulating NF-kappa B/TGF-beta/Smad signaling pathways
期刊论文
EXPERIMENTAL LUNG RESEARCH, 2022, 卷号: 48
Authors:
Zhou, Xia
;
Bao, Wu-An
;
Zhu, Xiang
;
Lin, Juan
;
Fan, Ju-Fen
;
Yang, Yang
;
Du, Xiang-Hui
;
Wang, Yue-Zhen
Favorite
  |  
View/Download:42/0
  |  
Submit date:2022/12/23
3,3 '-Diindolylmethane
inflammatory
NF-kappa B
pulmonary fibrosis
radiation-induced lung injury
TGF beta/Smad pathway
The Modulation of Chaihu Shugan Formula on Microbiota Composition in the Simulator of the Human Intestinal Microbial Ecosystem Technology Platform and its Influence on Gut Barrier and Intestinal Immunity in Caco-2/THP1-Blue (TM) Cell Co-Culture Model
期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
Authors:
Liu, Ling
;
Lu, Yi
;
Xu, Chao
;
Chen, Haitao
;
Wang, Xuanying
;
Wang, Yijie
;
Cai, Biyu
;
Li, Bing
;
Verstrepen, Lynn
;
Ghyselinck, Jonas
;
Marzorati, Massimo
;
Yao, Qinghua
Favorite
  |  
View/Download:52/0
  |  
Submit date:2022/05/16
chaihu shugan formula
gut microbiota
gut barrier
intestinal immunity
SHIMS (R) platform
human
HMGB1 augments cognitive impairment in sepsis-associated encephalopathy by binding to MD-2 and promoting NLRP3-induced neuroinflammation
期刊论文
PSYCHOGERIATRICS, 2021
Authors:
Xiong, Yanan
;
Yang, Jilin
;
Tong, Haiyang
;
Zhu, Chenting
;
Pang, Yinhu
Favorite
  |  
View/Download:60/0
  |  
Submit date:2022/01/25
cognitive impairment
HMGB1
MD-2
neuroinflammation
NLRP3
sepsis-associated encephalopathy
Caspase-3-mediated GSDME induced Pyroptosis in breast cancer cells through the ROS/JNK signalling pathway
期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2021
Authors:
Zhang, Ziwen
;
Zhang, Han
;
Li, Dongbo
;
Zhou, Xiaoping
;
Qin, Qi
;
Zhang, Qingyuan
Favorite
  |  
View/Download:60/0
  |  
Submit date:2021/09/06
breast cancer
doxorubicin
GSDME
pyroptosis
ROS
JNK pathway
Inhibiting NLRP3 inflammasome activation prevents copper-induced neuropathology in a murine model of Wilson's disease
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12
Authors:
Dong, Jianjian
;
Wang, Xun
;
Xu, Chenchen
;
Gao, Manli
;
Wang, Shijing
;
Zhang, Jin
;
Tong, Haiyang
;
Wang, Lulu
;
Han, Yongzhu
;
Cheng, Nan
;
Han, Yongsheng
Favorite
  |  
View/Download:103/0
  |  
Submit date:2021/03/15