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Aberrant copper metabolism and hepatic inflammation cause neurological manifestations in a mouse model of Wilson's disease 期刊论文
JOURNAL OF NEUROINFLAMMATION, 2024, 卷号: 21
Authors:  Dong, Jianjian;  Xiang, Guanghai;  Xia, Xiaoxue;  Xu, Lewen;  Wen, Peihua;  Xu, Chenchen;  Xu, Yin;  Su, Yushuang;  Song, Yanze;  Tong, Haiyang;  Zhu, Qingjun;  Han, Yongzhu;  Han, Yongsheng;  Cheng, Nan;  Wang, Haoyi;  Zhou, Hong
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Wilson's disease  ATP7B gene  R778L point mutation  Hepatic inflammation  Neurological manifestations  CRISPR/Cas9  
Activin A plays an essential role in migration and proliferation of hepatic stellate cells via Smad3 and calcium signaling 期刊论文
SCIENTIFIC REPORTS, 2024, 卷号: 14
Authors:  Zhang, Wei;  Zhu, Linjing;  Fang, Fang;  Zhang, Fenglin;  Wang, Runnan;  Yang, Ke;  Liu, Yahui;  Cui, Xueling
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Hepatic stellate cells  Proliferation  Migration  Activin A  Smad3  Calcium signaling  
Discovery of Pyrazolo[1,5-a]pyridine Derivatives as Potent and Selective PI3Kγ/δ Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2024
Authors:  Wang, Chun;  Zou, Fengming;  Qi, Ziping;  Liu, Qingwang;  Shen, Lijuan;  Yuan, Xinyu;  Deng, Maoqing;  Wang, Aoli;  Wang, Beilei;  Wang, Li;  Liang, Xiaofei;  Liu, Qingsong;  Liu, Jing
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A novel PDGFR inhibitor WQ-C-401 prevents pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension 期刊论文
EXPERIMENTAL CELL RESEARCH, 2024, 卷号: 441
Authors:  Huang, Wen;  Zhou, Hong;  He, Yiting;  Wang, Aoli;  Wang, Beilei;  Chen, Yongfei;  Liu, Chenyang;  Wang, Hong;  Xie, Weiping;  Kong, Hui
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WQ-C-401  Pulmonary arterial hypertension  Pulmonary vascular remodeling  Platelet-derived growth factor receptor  Smooth muscle cells  
Mechanism of Astragalus mongholicus Bunge ameliorating cerebral ischemia-reperfusion injury: Based on network pharmacology analysis and experimental verification 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 329
Authors:  Li, Rui;  Lou, Qi;  Ji, Tingting;  Li, Yincan;  Yang, Haoran;  Ma, Zheng;  Zhu, Yu;  Qian, Can;  Yang, Wulin;  Wang, Yijun;  Luo, Shengyong
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Astragalus mongholicus Bunge  Network pharmacology  Cerebral ischemia-reperfusion injury  GEO database  Molecular docking  
Sevoflurane enhances autophagy via Rac1 to attenuate lung ischaemia-reperfusion injury 期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2024, 卷号: 397
Authors:  Ding, Xian;  Gao, Xiang;  Ren, Aolin;  Xu, Jingjing;  Jiang, Xuliang;  Liang, Xiao;  Xie, Kangjie;  Zhou, Yan;  Hu, Chunxiao;  Huang, Dongxiao
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Lung ischaemia-reperfusion injury  Sevoflurane  Rac1  Autophagy  
A patent review of P2X7 receptor antagonists to treat inflammatory diseases (2018-present) 期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2024, 卷号: 34
Authors:  Iqbal, Jamshed;  Bano, Sehrish;  Khan, Imtiaz Ali;  Huang, Qing
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drug discovery  inflammation  heterocyclic compounds  calcium flux assay  
Daqing formula ameliorated allergic asthma and airway dysbacteriosis in mice challenged with ovalbumin and ampicillin 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 318
Authors:  Wu, Li-ren;  Peng, Qian-Yu;  Li, Xue-Jian;  Guo, Mei-Ying;  He, Jia-Qi;  Ying, Hua-Zhong;  Yu, Chen-Huan
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Lung dysbiosis  Th1/Th2 balance  Antibiotic  GSK-3 ss  
The Rostral Ventromedial and Lateral Medulla Are the Major Areas Responsive to Lung Cancer Progression among Brainstem Lung-Innervating Nuclei 期刊论文
BRAIN SCIENCES, 2022, 卷号: 12
Authors:  Chen, Mo;  Jiao, Yingfu;  Shi, Yumiao;  Xu, Saihong;  Tang, Dan;  Chen, Sihan;  Gao, Po;  Zhang, Xindi;  Zhao, Xiaojing;  Cai, Mengmeng;  Yu, Weifeng;  Xie, Kangjie
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lung cancer  brain-lung axis  crosstalk  brainstem nuclei  vagal core  c-Fos  pseudorabies virus  retrograde tracing  neural circuit  
Hypoxia-inducible factor 1-alpha is a driving mechanism linking chronic obstructive pulmonary disease to lung cancer 期刊论文
FRONTIERS IN ONCOLOGY, 2022, 卷号: 12
Authors:  Xu, Yuan-rui;  Wang, An-long;  Li, Ya-qing
Favorite  |  View/Download：55/0  |  Submit date：2022/12/23
chronic obstructive pulmonary disease  lung cancer  non-small cell lung cancer  hypoxia-inducible factor 1-alpha  hypoxia-inducible factor 1