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Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy 期刊论文
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13
作者:  Hua, Chen;  Shena, Lijuan;  Zoua, Fengming;  Wua, Yun;  Wanga, Beilei;  Wanga, Aoli;  Wud, Chao;  Wanga, Li;  Liua, Jing;  Wanga, Wenchao;  Liua, Qingsong
收藏  |  浏览/下载：27/0  |  提交时间：2023/11/10
Acquired resistance mutations  CDK9 inhibitors  Transcription  Single nucleotide polymorphisms  BAY1251152  
Discovery of Pyrrolo[2,3-d]pyrimidine derivatives as potent and selective colony stimulating factor 1 receptor kinase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243
作者:  Liang, Xiaofei;  Wang, Chun;  Wang, Beilei;  Liu, Juan;  Qi, Shuang;  Wang, Aoli;  Liu, Qingwang;  Deng, Maoqing;  Wang, Li;  Liu, Jing;  Liu, Qingsong
收藏  |  浏览/下载：38/0  |  提交时间：2022/12/23
CSF1R inhibitor  Kinase inhibitor  Macrophage polarization  
Pulmonary Salivary Gland Tumor, Mucoepidermoid Carcinoma: A Literature Review 期刊论文
JOURNAL OF ONCOLOGY, 2022, 卷号: 2022
作者:  Hu, Shumin;  Gong, Jiali;  Zhu, Xiu;  Lu, Hongyang
收藏  |  浏览/下载：33/0  |  提交时间：2022/12/23
Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Wang, Zuo-wei;  Zou, Feng-ming;  Wang, Ao-li;  Yang, Jing;  Jin, Rui;  Wang, Bei-lei;  Shen, Li-juan;  Qi, Shuang;  Liu, Juan;  Liu, Jing;  Wang, Wen-chao;  Liu, Qing-song
收藏  |  浏览/下载：39/0  |  提交时间：2022/12/22
AZD4547  RIPK1  inhibitors  SIRS model  anti-necroptosis  
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2 期刊论文
EMBO REPORTS, 2022
作者:  Li, Hui;  Wang, Ning;  Jiang, Yu;  Wang, Haofei;  Xin, Zengfeng;  An, Huazhang;  Pan, Hao;  Ma, Wangqian;  Zhang, Ting;  Wang, Xiaojian;  Lin, Wenlong
收藏  |  浏览/下载：30/0  |  提交时间：2022/12/22
IL-17R signaling  inflammation  MEKK2  NEDD4L  ubiquitination  
Expert consensus on the diagnosis and treatment of NTRK gene fusion solid tumors in China 期刊论文
THORACIC CANCER, 2022
作者:  Xu, Chunwei;  Si, Lu;  Wang, Wenxian;  Li, Ziming;  Song, Zhengbo;  Wang, Qian;  Liu, Aijun;  Yu, Jinpu;  Fang, Wenfeng;  Zhong, Wenzhao;  Wang, Zhijie;  Zhang, Yongchang;  Liu, Jingjing;  Zhang, Shirong;  Cai, Xiuyu;  Liu, Anwen;  Li, Wen;  Zhan, Ping;  Liu, Hongbing;  Lv, Tangfeng;  Miao, Liyun;  Min, Lingfeng;  Chen, Yu;  Yuan, Jingping;  Wang, Feng;  Jiang, Zhansheng;  Lin, Gen;  Pu, Xingxiang;  Lin, Rongbo;  Liu, Weifeng;  Rao, Chuangzhou;  Lv, Dongqing;  Yu, Zongyang;  Lei, Lei;  Li, Xiaoyan;  Tang, Chuanhao;  Zhou, Chengzhi;  Zhang, Junping;  Xue, Junli;  Guo, Hui;  Chu, Qian;  Meng, Rui;  Wu, Jingxun;  Zhang, Rui;  Hu, Xiao;  Zhou, Jin;  Zhu, Zhengfei;  Li, Yongheng;  Qiu, Hong;  Xia, Fan;  Lu, Yuanyuan;  Chen, Xiaofeng;  Ge, Rui;  Dai, Enyong;  Han, Yu;  Pan, Weiwei;  Luo, Jiancheng;  Jia, Hongtao;  Dong, Xiaowei;  Pang, Fei;  Wang, Kai;  Wang, Liping;  Zhu, Youcai;  Xie, Yanru;  Lin, Xinqin;  Cai, Jing;  Wei, Jia;  Lan, Fen;  Feng, Huijing;  Wang, Lin;  Du, Yingying;  Yao, Wang;  Shi, Xuefei;  Niu, Xiaomin;  Yuan, Dongmei;  Yao, Yanwen;  Huang, Jianhui;  Zhang, Yinbin;  Sun, Pingli;  Wang, Hong;  Ye, Mingxiang;  Wang, Dong;  Wang, Zhaofeng;  Wan, Bing;  Lv, Donglai;  Wei, Qing;  Kang, Jin;  Zhang, Jiatao;  Zhang, Chao;  Yu, Genhua;  Ou, Juanjuan;  Shi, Lin;  Li, Zhongwu;  Liu, Zhefeng;  Liu, Jing;  Yang, Nong;  Wu, Lin;  Wang, Huijuan;  Jin, Gu;  Yang, Liu;  Wang, Guansong;  Fang, Meiyu;  Fang, Yong;  Li, Yuan;  Wang, Xiaojia;  Zhang, Yiping;  Ma, Shenglin;  Wang, Biyun;  Zhang, Xiaotian;  Song, Yong;  Lu, Yuanzhi
收藏  |  浏览/下载：38/0  |  提交时间：2022/12/22
fusion  precision medicine  solid tumor  targeted therapy  tyrosine receptor kinase  
Systemic Therapy for Hepatocellular Carcinoma: Chinese Consensus-Based Interdisciplinary Expert Statements 期刊论文
LIVER CANCER, 2022, 卷号: 11
作者:  Sun, Yongkun;  Zhang, Wen;  Bi, Xinyu;  Yang, Zhengqiang;  Tang, Yu;  Jiang, Liming;  Bi, Feng;  Chen, Minshan;  Cheng, Shuqun;  Chi, Yihebali;  Han, Yue;  Huang, Jing;  Huang, Zhen;  Ji, Yuan;  Jia, Liqun;  Jiang, Zhichao;  Jin, Jing;  Jin, Zhengyu;  Li, Xiao;  Li, Zhiyu;  Liang, Jun;  Liu, Lianxin;  Liu, Yunpeng;  Lu, Yinying;  Lu, Shichun;  Meng, Qinghua;  Niu, Zuoxing;  Pan, Hongming;  Qin, Shukui;  Qu, Wang;  Shao, Guoliang;  Shen, Feng;  Song, Tianqiang;  Song, Yan;  Tao, Kaishan;  Tian, Aiping;  Wang, Jianhua;  Wang, Wenling;  Wang, Zhe;  Wu, Liqun;  Xia, Feng;  Xing, Baocai;  Xu, Jianming;  Xue, Huadan;  Yan, Dong;  Yang, Lin;  Ying, Jianming;  Yun, Jingping;  Zeng, Zhaochong;  Zhang, Xuewen;  Zhang, Yanqiao;  Zhang, Yefan;  Zhao, Jianjun;  Zhou, Jianguo;  Zhu, Xu;  Zou, Yinghua;  Dong, Jiahong;  Fan, Jia;  Lau, Wan Yee;  Sun, Yan;  Yu, Jinming;  Zhao, Hong;  Zhou, Aiping;  Cai, Jianqiang
收藏  |  浏览/下载：35/0  |  提交时间：2022/12/23
Chinese interdisciplinary experts  Hepatocellular carcinoma  Molecular targeted therapy  Consensus  
Efficacy and safety of anlotinib with and without EGFR-TKIs or immunotherapy in the treatment of elder patients with non-small-cell lung cancer: a retrospective study 期刊论文
BMC PULMONARY MEDICINE, 2022, 卷号: 22
作者:  Wang, Wenxian;  Shao, Lan;  Xu, Yibing;  Song, Zhengbo;  Lou, Guangyuan;  Zhang, Yiping;  Chen, Ming
收藏  |  浏览/下载：24/0  |  提交时间：2022/12/23
Non-small cell lung cancer  Prognosis  Angiogenesis  Tyrosine kinase inhibitors  
Treatment outcomes and prognosis of patients with primary and acquired BRAF-mutated non-small cell lung cancer: A multicenter retrospective study 期刊论文
GENES CHROMOSOMES & CANCER, 2022
作者:  Wang, Wenxian;  Gu, Xiaodong;  Si, Jinfei;  Pu, Xingxiang;  Wang, Liping;  Chen, Huafei;  Xu, Chunwei;  Zhang, Xiaoyan;  Yuan, Hongling;  Lou, Guangyuan;  Shao, Lan;  Zhang, Gu;  Song, Zhengbo
收藏  |  浏览/下载：46/0  |  提交时间：2022/05/16
BRAF mutation  immune checkpoint inhibitors  non-small cell lung cancer  PD-L1  targeted therapy  
HER2 exon 20 insertion mutations in lung adenocarcinoma with leptomeningeal metastasis: a case report and response to poziotinib 期刊论文
ANNALS OF PALLIATIVE MEDICINE, 2022, 卷号: 11
作者:  Fan, Ying;  Qin, Jing;  Han, Na;  Lu, Hongyang
收藏  |  浏览/下载：24/0  |  提交时间：2022/12/23
Leptomeningeal metastasis (LM)  cerebrospinal fluid  HER2 exon 20 insertion mutations  poziotinib  case report