中文版 | English

在结果中检索

HFCAS OpenIR

浏览/检索结果: 共25条，第1-10条 帮助

限定条件    
已选(0)清除 条数/页：   排序方式：
Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 43, 页码: 69760-69769
作者:  Wang, Aoli;  Yan, Xiao-E;  Wu, Hong;  Wang, Wenchao;  Hu, Chen;  Chen, Cheng;  Zhao, Zheng;  Zhao, Peng;  Li, Xixiang;  Wang, Li;  Wang, Beilei;  Ye, Zi;  Wang, Jinhua;  Wang, Chu;  Zhang, Wei;  Gray, Nathanael S.;  Weisberg, Ellen L.;  Chen, Liang;  Liu, Jing;  Yun, Cai-Hong;  Liu, Qingsong
浏览  |  Adobe PDF(2026Kb)  |  收藏  |  浏览/下载：130/67  |  提交时间：2017/11/21
Ibrutinib  Egfr Kinase  Dfg-in/c-helix-out  Inactive Conformation  Nsclc  
Discovery of a highly potent FLT3 kinase inhibitor for FLT3-ITD-positive AML 期刊论文
LEUKEMIA, 2016, 卷号: 30, 期号: 10, 页码: 2112-2116
作者:  Wu, H.;  Wang, A.;  Qi, Z.;  Li, X.;  Chen, C.;  Yu, K.;  Zou, F.;  Hu, C.;  Wang, W.;  Zhao, Z.;  Wu, J.;  Liu, J.;  Liu, X.;  Wang, L.;  Wang, W.;  Zhang, S.;  Stone, R. M.;  Galinsky, I. A.;  Griffin, J. D.;  Weinstock, D.;  Christodoulou, A.;  Wang, H.;  Shen, Y.;  Zhai, Z.;  Weisberg, E. L.;  Liu, J.;  Liu, Q.
浏览  |  Adobe PDF(1142Kb)  |  收藏  |  浏览/下载：115/74  |  提交时间：2017/11/21
Discovery of N-((1-(4-(3-(3-((6,7-Dimethoxyquinolin-3-yl)oxy)phenyl)ureido)-2-(trifluoromethyl)phenyl)piperidin-4-yl)methyl)propionamide (CHMFL-KIT-8140) as a Highly Potent Type II Inhibitor Capable of Inhibiting the T670I "Gatekeeper" Mutant of cKIT Kinase 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 18, 页码: 8456-8472
作者:  Li, Binhua;  Wang, Aoli;  Liu, Juan;  Qi, Ziping;  Liu, Xiaochuan;  Yu, Kailin;  Wu, Hong;  Chen, Cheng;  Hu, Chen;  Wang, Wenchao;  Wu, Jiaxin;  Hu, Zhenquan;  Ye, Ling;  Zou, Fengming;  Liu, Feiyang;  Wang, Beilei;  Wang, Li;  Ren, Tao;  Zhang, Shaojuan;  Bai, Mingfeng;  Zhang, Shanchun;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(2856Kb)  |  收藏  |  浏览/下载：1414/1300  |  提交时间：2017/11/21
Sub-molecular features of single proteins in solution resolved with scanning tunneling microscopy 期刊论文
NANO RESEARCH, 2016, 卷号: 9, 期号: 9, 页码: 2551-2560
作者:  Wang, Jihao;  Zhang, Lei;  Hu, Chen;  Liu, Qingsong;  Hou, Yubin;  Zhang, Xin;  Lu, Qingyou
浏览  |  Adobe PDF(1895Kb)  |  收藏  |  浏览/下载：85/42  |  提交时间：2017/11/21
Liquid-phase Scanning Tunneling Microscopy (Stm)  Stm Imaging Under Physiological Conditions  Protein Molecule  Sub-molecular Resolution  
Simultaneous inhibition of Vps34 kinase would enhance PI3K delta inhibitor cytotoxicity in the B-cell malignancies 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 33, 页码: 53515-53525
作者:  Liu, Xiaochuan;  Wang, Aoli;  Liang, Xiaofei;  Liu, Juanjuan;  Zou, Fengming;  Chen, Cheng;  Zhao, Zheng;  Deng, Yuanxin;  Wu, Hong;  Qi, Ziping;  Wang, Beilei;  Wang, Li;  Liu, Feiyang;  Xu, Yunhe;  Wang, Wenchao;  Fernandes, Stacey M.;  Stone, Richard M.;  Galinsky, Ilene A.;  Brown, Jennifer R.;  Loh, Teckpeng;  Griffin, James. D.;  Zhang, Shanchun;  Weisberg, Ellen L.;  Zhang, Xin;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(7625Kb)  |  收藏  |  浏览/下载：103/39  |  提交时间：2017/11/21
Pi3k Delta  Vps34  Combination  Chronic Lymphatic Leukemia  Acute Myeloid Leukemia  
Progress on Molecular Mechanism of Phosphorylation/Dephosphorylation and Detection Technology of gamma H2AX 期刊论文
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2016, 卷号: 44, 期号: 8, 页码: 1291-1299
作者:  Zhang Sen;  Liu Lu-Juan;  Chen Huan;  Hou Hong-Wei;  Hu Qing-Yuan
浏览  |  Adobe PDF(2969Kb)  |  收藏  |  浏览/下载：149/60  |  提交时间：2017/11/17
Gamma H2ax  Phosphorylation  Immunofluorescence Technology  Toxicity Evaluation  Review  
Discovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML) 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 29, 页码: 45562-45574
作者:  Liu, Feiyang;  Wang, Beilei;  Wang, Qiang;  Qi, Ziping;  Chen, Cheng;  Kong, Lu-Lu;  Chen, Ji-Yun;  Liu, Xiaochuan;  Wang, Aoli;  Hu, Chen;  Wang, Wenchao;  Wang, Huiping;  Wu, Fan;  Ruan, Yanjie;  Qi, Shuang;  Liu, Juan;  Zou, Fengming;  Hu, Zhenquan;  Wang, Wei;  Wang, Li;  Zhang, Shanchun;  Yun, Cai-Hong;  Zhai, Zhimin;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(8054Kb)  |  收藏  |  浏览/下载：258/203  |  提交时间：2017/11/21
Bcr-abl  Pdgfr  Chronic Myeloid Leukemia  Kinase Inhibitor  
Moderate and strong static magnetic fields directly affect EGFR kinase domain orientation to inhibit cancer cell proliferation 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 27, 页码: 41527-41539
作者:  Zhang, Lei;  Wang, Jihao;  Wang, HongLei;  Wang, Wenchao;  Li, Zhiyuan;  Liu, Juanjuan;  Yang, Xingxing;  Ji, Xinmiao;  Luo, Yan;  Hu, Chen;  Hou, Yubin;  He, Qianqian;  Fang, Jun;  Wang, Junfeng;  Liu, Qingsong;  Li, Guohui;  Lu, Qingyou;  Zhang, Xin
浏览  |  Adobe PDF(11191Kb)  |  收藏  |  浏览/下载：108/45  |  提交时间：2017/11/21
Egfr  Magnetic Field  Stm  Cancer  
Characterization of selective and potent PI3K delta inhibitor (PI3KD-IN-015) for B-Cell malignances 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 22, 页码: 32641-32651
作者:  Liu, Xiaochuan;  Wang, Aoli;  Liang, Xiaofei;  Chen, Cheng;  Liu, Juanjuan;  Zhao, Zheng;  Wu, Hong;  Deng, Yuanxin;  Wang, Li;  Wang, Beilei;  Wu, Jiaxin;  Liu, Feiyang;  Fernandes, Stacey M.;  Adamia, Sophia;  Stone, Richard M.;  Galinsky, Ilene A.;  Brown, Jennifer R.;  Griffin, James D.;  Zhang, Shanchun;  Loh, Teckpeng;  Zhang, Xin;  Wang, Wenchao;  Weisberg, Ellen L.;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(5138Kb)  |  收藏  |  浏览/下载：89/30  |  提交时间：2017/11/16
Pi3k Delta  Leukemia  B-cell Malignances  Pi3k  Kinase Inhibitors  
Dual Inhibition of AKT/FLT3-ITD by A674563 Overcomes FLT3 Ligand-Induced Drug Resistance in FLT3-ITD positive AML 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 20, 页码: 29131-29142
作者:  Wang, Aoli;  Wu, Hong;  Chen, Cheng;  Hu, Chen;  Qi, Ziping;  Wang, Wenchao;  Yu, Kailin;  Liu, Xiaochuan;  Zou, Fengming;  Zhao, Zheng;  Wu, Jiaxin;  Liu, Juan;  Liu, Feiyang;  Wang, Li;  Stone, Richard M.;  Galinksy, Ilene A.;  Griffin, James D.;  Zhang, Shanchun;  Weisberg, Ellen L.;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(4786Kb)  |  收藏  |  浏览/下载：138/36  |  提交时间：2017/11/16
Acute Myeloid Leukemia  Flt3-itd  Akt  A6745763  Flt3-ligand