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Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop 期刊论文
NUTRIENTS, 2022, 卷号: 14
作者:  Tang, Hengfang;  Zheng, Zhiming;  Wang, Han;  Wang, Li;  Zhao, Genhai;  Wang, Peng
收藏  |  浏览/下载：51/0  |  提交时间：2022/05/16
vitamin K2  apoptosis  ROS  mitochondrial dysfunction  mitophagy  mitochondrial biogenesis  mitochondrial quality-control loop  PINK1  Parkin signaling pathway  
CHMFL-26 is a highly potent irreversible HER2 inhibitor for use in the treatment of HER2-positive and HER2-mutant cancers 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Cao, Jiang-yan;  Qi, Shuang;  Wu, Hong;  Wang, Ao-li;  Liu, Qing-wang;  Li, Xi-xiang;  Wang, Bei-lei;  Ge, Juan;  Zou, Feng-ming;  Chen, Cheng;  Wang, Jun-jie;  Hu, Chen;  Liu, Jing;  Wang, Wen-chao;  Liu, Qing-song
收藏  |  浏览/下载：92/0  |  提交时间：2022/03/28
HER2  breast cancers  gastric cancers  irreversible inhibitor  drug resistance  
Comparative transcriptome analysis providing inhibitory mechanism of lung cancer A549 cells by radioactive I-125 seed 期刊论文
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, 2021
作者:  Liu, Fang;  Bao, Jie;  Chen, Jinwu;  Song, Wencheng
收藏  |  浏览/下载：54/0  |  提交时间：2021/11/01
I-125 seed  Transcriptome  Inhibitory mechanism  A549 cells  
Gradient radiation breeding and culture domestication of menaquinone producing strains 期刊论文
BIOPROCESS AND BIOSYSTEMS ENGINEERING, 2021
作者:  Wu, Hefang;  Wang, Han;  Wang, Peng;  Zhao, Geihai;  Liu, Hui;  Wang, Li;  Sun, Xiaowen;  Zheng, Zhiming
收藏  |  浏览/下载：43/0  |  提交时间：2021/06/15
Biofilm lipid peroxidation  Gamma ray mutagenesis  Low-energy ion implantation  Menaquinone (MK)  SOD activity  
Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML) 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 897
作者:  Lu, Tingting;  Cao, Jiangyan;  Zou, Fengming;  Li, Xixiang;  Wang, Aoli;  Wang, Wenliang;  Liang, Huamin;  Liu, Qingwang;  Hu, Chen;  Chen, Cheng;  Hu, Zhenquan;  Wang, Wenchao;  Li, Lili;  Ge, Jian;  Shen, Yang;  Ren, Tao;  Liu, Jing;  Xia, Ruixiang;  Liu, Qingsong
收藏  |  浏览/下载：67/0  |  提交时间：2021/04/26
BCR-ABL  ABL mutants  Chronic myeloid leukemia  Kinase inhibitor  Imatinib resistance  
Inhibiting NLRP3 inflammasome activation prevents copper-induced neuropathology in a murine model of Wilson's disease 期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12
作者:  Dong, Jianjian;  Wang, Xun;  Xu, Chenchen;  Gao, Manli;  Wang, Shijing;  Zhang, Jin;  Tong, Haiyang;  Wang, Lulu;  Han, Yongzhu;  Cheng, Nan;  Han, Yongsheng
收藏  |  浏览/下载：87/0  |  提交时间：2021/03/15
Mutagenicity of 7-ketocholesterol in CHO cells: The role of lipid peroxidation 期刊论文
TOXICOLOGY, 2020, 卷号: 446
作者:  Wang, Xiaofei;  Li, Yintao;  Xia, Xuanyi;  Zhang, Min;  Ge, Chunmei;  Xia, Xiaoxiao;  Xiao, Hourong;  Xu, Shengmin
收藏  |  浏览/下载：46/0  |  提交时间：2020/12/28
7-ketocholesterol  Mutagenicity  DNA damage  Apoptosis  Lipid peroxidation  
Combinations of proteasome inhibitors with obatoclax are effective for small cell lung cancer 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020
作者:  Yin, Yan-ping;  Shi, Wen-hao;  Deng, Ke;  Liu, Xiao-li;  Li, Hong;  Lv, Xiao-tong;  Lui, Vivian Wai Yan;  Ding, Chen;  Hong, Bo;  Lin, Wen-chu
收藏  |  浏览/下载：49/0  |  提交时间：2020/12/28
small cell lung cancer  obatoclax  bortezomib  carfilzomib  MCL-1  apoptosis  FOXM1  proteomics analysis  
Applications of atmospheric pressure plasma in microbial inactivation and cancer therapy: a brief review 期刊论文
PLASMA SCIENCE & TECHNOLOGY, 2020, 卷号: 22
作者:  Xu, Zimu;  Lan, Yan;  Ma, Jie;  Shen, Jie;  Han, Wei;  Hu, Shuheng;  Ye, Chaobing;  Xi, Wenhao;  Zhang, Yudi;  Yang, Chunjun;  Zhao, Xiao;  Cheng, Cheng
收藏  |  浏览/下载：43/0  |  提交时间：2020/10/26
atmospheric pressure plasma  plasma medicine  reactive species  bacteria  cancer cells  
Genotoxicity of microcystin-LR in mammalian cells: Implication from peroxynitrite produced by mitochondria 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 195
作者:  Wang, Xiaofei;  Li, Yintao;  Xiao, Hourong;  Zhang, Min;  Bao, Teng;  Luo, Xun;  Chen, Shaopeng
收藏  |  浏览/下载：34/0  |  提交时间：2020/11/26
Microcystin-LR  DNA damage  Peroxynitrite  Mitochondria