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Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen;  Wu, Hong;  Zhang, Yicong;  Liu, Xiaochuan;  Wang, Wenliang;  Wang, Junjie;  Hu, Zhenquan;  Wang, Aoli;  Huang, Tao;  Liu, Qingwang;  Wang, Wei;  Wang, Li;  Wang, Wenchao;  Ren, Tao;  Li, Lili;  Xia, Ruixiang;  Ge, Jian;  Liu, Qingsong;  Liu, Jing
Adobe PDF(4593Kb)  |  收藏  |  浏览/下载：190/104  |  提交时间：2019/01/11
ABL kinase  Kinase inhibitor  ABL mutant  CML  
Disruption of Chromosomal Architecture of cox2 Locus Sensitizes Lung Cancer Cells to Radiotherapy 期刊论文
MOLECULAR THERAPY, 2018, 卷号: 26, 期号: 10, 页码: 2456-2465
作者:  Sun, Yuxiang;  Dai, Hui;  Chen, Shaopeng;  Zhang, Yajun;  Wu, Tao;  Cao, Xianbin;  Zhao, Guoping;  Xu, An;  Wang, Jun;  Wu, Lijun
收藏  |  浏览/下载：25/0  |  提交时间：2019/12/25
Biological effects on cells in strong static magnetic field 期刊论文
ACTA PHYSICA SINICA, 2018, 卷号: 67, 期号: 14, 页码: 11
作者:  Tian Xiao-Fei;  Zhang Xin
收藏  |  浏览/下载：23/0  |  提交时间：2019/12/10
high static magnetic fields  cell orientation  cell proliferation  cell type  
Supervillin promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma in hypoxia via activation of the RhoA/ROCK-ERK/p38 pathway 期刊论文
Journal of Experimental & Clinical Cancer Research, 2018, 卷号: 37
作者:  Chen,Xueran;  Zhang,Shangrong;  Wang,Zhen;  Wang,Fengsong;  Cao,Xinwang;  Wu,Quan;  Zhao,Chenggang;  Ma,Huihui;  Ye,Fang;  Wang,Hongzhi;  Fang,Zhiyou
收藏  |  浏览/下载：27/0  |  提交时间：2020/10/21
Supervillin  RhoA/ROCK  ERK/P38  EMT  HCC  
Carbon-based hybrid nanogels: a synergistic nanoplatform for combined biosensing, bioimaging, and responsive drug delivery 期刊论文
CHEMICAL SOCIETY REVIEWS, 2018, 卷号: 47, 期号: 11, 页码: 4198-4232
作者:  Wang, Hui;  Chen, Qianwang;  Zhou, Shuiqin
浏览  |  Adobe PDF(6297Kb)  |  收藏  |  浏览/下载：103/27  |  提交时间：2019/11/12
Discovery of 4,7-Diamino-5-(4-phenoxyphenyl)-6-methylene-pyrinnido[5,4-b]pyrrolizines as Novel Bruton's Tyrosine Kinase Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 10, 页码: 4608-4627
作者:  Xue, Yu;  Song, Peiran;  Song, Zilan;  Wang, Aoli;  Tong, Linjiang;  Geng, Meiyu;  Ding, Jian;  Liu, Qingsong;  Sun, Liping;  Xie, Hua;  Zhang, Ao
浏览  |  Adobe PDF(6587Kb)  |  收藏  |  浏览/下载：147/106  |  提交时间：2019/08/23
A plug-in electrophoresis microchip with PCB electrodes for contactless conductivity detection 期刊论文
ROYAL SOCIETY OPEN SCIENCE, 2018, 卷号: 5, 期号: 5, 页码: 9
作者:  Yang, Mingpeng;  Huang, Zhe;  You, Hui
浏览  |  Adobe PDF(927Kb)  |  收藏  |  浏览/下载：92/53  |  提交时间：2019/11/12
electrophoresis  microchip  plug-in structure  
Dysembryoplastic neuroepithelial tumor-like pilocytic astrocytoma: A case report 期刊论文
MEDICINE, 2018, 卷号: 97, 期号: 20, 页码: 4
作者:  Liao, Jia-Ming;  Wang, Wei;  Xie, Jing;  Wu, Hai-Bo
浏览  |  Adobe PDF(530Kb)  |  收藏  |  浏览/下载：65/26  |  提交时间：2019/08/26
dysembryoplastic neuroepithelial tumor  fluorescence in situ hybridisation  KIAA1549-BRAF fusion gene  pilocytic astrocytoma  
Development of Microchip Electrophoresis and Its Applications in Ion Detection 期刊论文
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2018, 卷号: 46, 期号: 5, 页码: 631-640
作者:  Yang Ming-Peng;  Huang Zhe;  Xie Yang;  You Hui
浏览  |  Adobe PDF(2107Kb)  |  收藏  |  浏览/下载：80/38  |  提交时间：2019/08/26
Microchip electrophoresis  Ion detection  Surface modification  Preconcentration  Review  
A Machine Learning Approach to Detecting of Freezing of Gait in Parkinson's Disease Patients 期刊论文
JOURNAL OF MEDICAL IMAGING AND HEALTH INFORMATICS, 2018, 卷号: 8, 期号: 4, 页码: 647-654
作者:  Xia, Yi;  Yao, ZhiMing;  Lu, Yixiang;  Zhang, Dexiang;  Cheng, Nan
浏览  |  Adobe PDF(6268Kb)  |  收藏  |  浏览/下载：66/21  |  提交时间：2019/08/26
Freezing of Gait (FOG)  Parkinson's Disease (PD)  Gait Classification  Feature Selection  Acceleration Signal