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Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Cao, Guo-Zhen;  Ma, Li-Ying;  Zhang, Zong-Hui;  Wang, Xiao-Lin;  Hua, Jing-Han;  Zhang, Jia-Hui;  Lv, Yang;  Zhang, Shao-Bo;  Ou, Jian;  Lin, Wen-Chu
收藏  |  浏览/下载：42/0  |  提交时间：2022/12/22
small-cell lung cancer  H3  3  PARP1  PARP inhibitor  darinaparsin  combination treatment  
Comprehensive analysis of the expression, prognosis, and immune infiltrates for CHDs in human lung cancer 期刊论文
DISCOVER ONCOLOGY, 2022, 卷号: 13
作者:  Lv, Yang;  Lin, Wenchu
收藏  |  浏览/下载：31/0  |  提交时间：2022/12/23
Lung cancer  CHD family  Prognosis  Bioinformatics analysis  Immune infiltrates  
CHMFL-26 is a highly potent irreversible HER2 inhibitor for use in the treatment of HER2-positive and HER2-mutant cancers 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Cao, Jiang-yan;  Qi, Shuang;  Wu, Hong;  Wang, Ao-li;  Liu, Qing-wang;  Li, Xi-xiang;  Wang, Bei-lei;  Ge, Juan;  Zou, Feng-ming;  Chen, Cheng;  Wang, Jun-jie;  Hu, Chen;  Liu, Jing;  Wang, Wen-chao;  Liu, Qing-song
收藏  |  浏览/下载：92/0  |  提交时间：2022/03/28
HER2  breast cancers  gastric cancers  irreversible inhibitor  drug resistance  
FK228 potentiates topotecan activity against small cell lung cancer cells via induction of SLFN11 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021
作者:  Yin, Yan-ping;  Ma, Li-ying;  Cao, Guo-zhen;  Hua, Jing-han;  Lv, Xiao-tong;  Lin, Wen-chu
收藏  |  浏览/下载：68/0  |  提交时间：2022/01/10
small cell lung cancer  topotecan  DNA damage response  FK228  SLFN11  methylation  epigenetic modulation  
Exosomal miR-92b-3p Promotes Chemoresistance of Small Cell Lung Cancer Through the PTEN/AKT Pathway 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9
作者:  Li, Ming;  Shan, Wulin;  Hua, Yan;  Chao, Fengmei;  Cui, Yayun;  Lv, Lei;  Dou, Xiaoyan;  Bian, Xing;  Zou, Jinglu;  Li, Hong;  Lin, Wenchu
收藏  |  浏览/下载：50/0  |  提交时间：2021/08/31
exosome  miR-92b-3p  small cell lung cancer  chemoresistance  migration  
FK228 sensitizes radioresistant small cell lung cancer cells to radiation 期刊论文
CLINICAL EPIGENETICS, 2021, 卷号: 13
作者:  Li, Hong;  Ma, Liying;  Bian, Xing;  Lv, Yang;  Lin, Wenchu
收藏  |  浏览/下载：37/0  |  提交时间：2021/04/26
Small cell lung cancer  FK228  Histone deacetylase  PI3K  Radioresistance  DNA damage repair  
Network-based analysis with primary cells reveals drug response landscape of acute myeloid leukemia 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 393
作者:  Chen, Cheng;  Wang, Li;  Li, Lili;  Wang, Aoli;  Huang, Tao;  Hu, Jie;  Zhao, Ming;  Liu, Feiyang;  Qi, Shuang;  Hu, Chen;  Wang, Wenliang;  Liu, Jing;  Ge, Jian;  Xia, Ruixiang;  Wang, Wenchao;  Liu, Qingsong
收藏  |  浏览/下载：37/0  |  提交时间：2020/11/26
Acute myeloid leukemia (AML)  Drug response  Gene mutations  
Circulating miR-92b and miR-375 for monitoring the chemoresistance and prognosis of small cell lung cancer 期刊论文
SCIENTIFIC REPORTS, 2020, 卷号: 10
作者:  Li, Ming;  Shan, Wulin;  Hong, Bo;  Zou, Jinglu;  Li, Hong;  Han, Dandan;  Zhang, Yang;  Li, Lailing;  Li, Dan;  Lin, Wenchu
收藏  |  浏览/下载：33/0  |  提交时间：2020/10/26
Osimertinib successfully combats EGFR-negative glioblastoma cells by inhibiting the MAPK pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020
作者:  Chen, Cheng;  Cheng, Chuan-dong;  Wu, Hong;  Wang, Zuo-wei;  Wang, Li;  Jiang, Zong-ru;  Wang, Ao-li;  Hu, Chen;  Dong, Yong-fei;  Niu, Wan-xiang;  Qi, Shuang;  Qi, Zi-ping;  Liu, Jing;  Wang, Wen-chao;  Niu, Chao-shi;  Liu, Qing-song
浏览  |  Adobe PDF(3476Kb)  |  收藏  |  浏览/下载：94/35  |  提交时间：2020/11/26
glioblastoma  osimertinib  temozolamide  MAPK-signaling pathway  MNK  eukaryotic translation initiation factor 4E