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Discovery of (R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2-(dimethylamino)ethanone (CHMFL-FLT3-122) as a Potent and Orally Available FLT3 Kinase Inhibitor for FLT3-ITD Positive Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 58, 期号: 24, 页码: 9625-9638
作者:  Li, Xixiang;  Wang, Aoli;  Yu, Kailin;  Qi, Ziping;  Chen, Cheng;  Wang, Wenchao;  Hu, Chen;  Wu, Hong;  Wu, Jiaxin;  Zhao, Zheng;  Liu, Juan;  Zou, Fengming;  Wang, Li;  Wang, Beilei;  Wang, Wei;  Zhang, Shanchun;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(6123Kb)  |  收藏  |  浏览/下载：158/100  |  提交时间：2017/10/25
1 T moderate intensity static magnetic field affects Akt/mTOR pathway and increases the antitumor efficacy of mTOR inhibitors in CNE-2Z cells 期刊论文
SCIENCE BULLETIN, 2015, 卷号: 60, 期号: 24, 页码: 2120-2128
作者:  Zhang, Lei;  Yang, Xingxing;  Liu, Juanjuan;  Luo, Yan;  Li, Zhiyuan;  Ji, Xinmiao;  Wang, Wenchao;  Zhang, Xin
浏览  |  Adobe PDF(627Kb)  |  收藏  |  浏览/下载：83/35  |  提交时间：2017/10/25
Static Magnetic Field  Cell Proliferation  Mtor  Mtor Inhibitor  Feedback Reactivation  
1T moderate intensity static magnetic field affects Akt/mTOR pathway and increases the antitumor efficacy of mTOR inhibitors in CNE-2Z cells 期刊论文
Sci. Bull., 2015, 卷号: 60, 期号: 24, 页码: 2120-2128
作者:  Lei Zhang;  Xingxing Yang;  Juanjuan Liu;  Yan Luo;  Zhiyuan Li;  Xinmiao Ji;  Wenchao Wang;  Xin Zhang
Adobe PDF(3399Kb)  |  收藏  |  浏览/下载：76/38  |  提交时间：2016/01/11