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HFCAS OpenIR

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Different conformational responses of the beta(2)-adrenergic receptor-Gs complex upon binding of the partial agonist salbutamol or the full agonist isoprenaline 期刊论文
NATIONAL SCIENCE REVIEW, 2021, 卷号: 8
作者:  Yang, Fan;  Ling, Shenglong;  Zhou, Yingxin;  Zhang, Yanan;  Lv, Pei;  Liu, Sanling;  Fang, Wei;  Sun, Wenjing;  Hu, Liaoyuan A.;  Zhang, Longhua;  Shi, Pan;  Tian, Changlin
收藏  |  浏览/下载：46/0  |  提交时间：2021/11/01
cryo-EM structure  G protein-coupled receptor (GPCR)  partial and full agonists  conformational change  desensitization  
Structures of wild-type and H451N mutant human lymphocyte potassium channel K(V)1.3 期刊论文
CELL DISCOVERY, 2021, 卷号: 7
作者:  Liu, Sanling;  Zhao, Yue;  Dong, Hao;  Xiao, Liang;  Zhang, Yong;  Yang, Yuqin;  Ong, Seow Theng;  Chandy, K. George;  Zhang, Longhua;  Tian, Changlin
收藏  |  浏览/下载：55/0  |  提交时间：2021/06/21
Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca2+ ions and L-tryptophan 期刊论文
CELL RESEARCH, 2021
作者:  Ling, Shenglong;  Shi, Pan;  Liu, Sanling;  Meng, Xianyu;  Zhou, Yingxin;  Sun, Wenjing;  Chang, Shenghai;  Zhang, Xing;  Zhang, Longhua;  Shi, Chaowei;  Sun, Demeng;  Liu, Lei;  Tian, Changlin
收藏  |  浏览/下载：42/0  |  提交时间：2021/04/26
Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1 期刊论文
ELIFE, 2020, 卷号: 9
作者:  Sun, Demeng;  Liu, Sanling;  Li, Siyu;  Zhang, Mengge;  Yang, Fan;  Wen, Ming;  Shi, Pan;  Wang, Tao;  Pan, Man;  Chang, Shenghai;  Zhang, Xing;  Zhang, Longhua;  Tian, Changlin;  Liu, Lei
收藏  |  浏览/下载：75/0  |  提交时间：2020/11/30
Cryo-EM structure of the hyperpolarization-activated inwardly rectifying potassium channel KAT1 from Arabidopsis 期刊论文
CELL RESEARCH, 2020
作者:  Li, Siyu;  Yang, Fan;  Sun, Demeng;  Zhang, Yong;  Zhang, Mengge;  Liu, Sanling;  Zhou, Peng;  Shi, Chaowei;  Zhang, Longhua;  Tian, Changlin
收藏  |  浏览/下载：36/0  |  提交时间：2020/11/30
A genetically encoded small-size fluorescent pair reveals allosteric conformational changes of G proteins upon its interaction with GPCRs by fluorescence lifetime based FRET 期刊论文
CHEMICAL COMMUNICATIONS, 2020, 卷号: 56
作者:  Shi, Pan;  Zhang, Yanan;  Lv, Pei;  Fang, Wei;  Ling, Shenglong;  Guo, Xiaoqi;  Li, Dong;  Liu, Sanling;  Sun, Demeng;  Zhang, Longhua;  Liu, Dongsheng;  Zheng, Ji-Shen;  Tian, Changlin
收藏  |  浏览/下载：19/0  |  提交时间：2020/10/26