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Different conformational responses of the beta(2)-adrenergic receptor-Gs complex upon binding of the partial agonist salbutamol or the full agonist isoprenaline 期刊论文
NATIONAL SCIENCE REVIEW, 2021, 卷号: 8
作者:  Yang, Fan;  Ling, Shenglong;  Zhou, Yingxin;  Zhang, Yanan;  Lv, Pei;  Liu, Sanling;  Fang, Wei;  Sun, Wenjing;  Hu, Liaoyuan A.;  Zhang, Longhua;  Shi, Pan;  Tian, Changlin
收藏  |  浏览/下载：46/0  |  提交时间：2021/11/01
cryo-EM structure  G protein-coupled receptor (GPCR)  partial and full agonists  conformational change  desensitization  
Cryo-EM structure of the hyperpolarization-activated inwardly rectifying potassium channel KAT1 from Arabidopsis 期刊论文
CELL RESEARCH, 2020
作者:  Li, Siyu;  Yang, Fan;  Sun, Demeng;  Zhang, Yong;  Zhang, Mengge;  Liu, Sanling;  Zhou, Peng;  Shi, Chaowei;  Zhang, Longhua;  Tian, Changlin
收藏  |  浏览/下载：34/0  |  提交时间：2020/11/30
Single-particle cryo-EM structural studies of the beta(2)AR-Gs complex bound with a full agonist formoterol 期刊论文
CELL DISCOVERY, 2020, 卷号: 6
作者:  Zhang, Yanan;  Yang, Fan;  Ling, Shenglong;  Lv, Pei;  Zhou, Yingxin;  Fang, Wei;  Sun, Wenjing;  Zhang, Longhua;  Shi, Pan;  Tian, Changlin
收藏  |  浏览/下载：45/0  |  提交时间：2020/11/23
A genetically encoded small-size fluorescent pair reveals allosteric conformational changes of G proteins upon its interaction with GPCRs by fluorescence lifetime based FRET 期刊论文
CHEMICAL COMMUNICATIONS, 2020, 卷号: 56
作者:  Shi, Pan;  Zhang, Yanan;  Lv, Pei;  Fang, Wei;  Ling, Shenglong;  Guo, Xiaoqi;  Li, Dong;  Liu, Sanling;  Sun, Demeng;  Zhang, Longhua;  Liu, Dongsheng;  Zheng, Ji-Shen;  Tian, Changlin
收藏  |  浏览/下载：19/0  |  提交时间：2020/10/26