中文版 | English

在结果中检索

HFCAS OpenIR

浏览/检索结果: 共17条，第1-10条 帮助

限定条件    
已选(0)清除 条数/页：   排序方式：
Discovery of Pyrrolo[2,3-d]pyrimidine derivatives as potent and selective colony stimulating factor 1 receptor kinase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243
作者:  Liang, Xiaofei;  Wang, Chun;  Wang, Beilei;  Liu, Juan;  Qi, Shuang;  Wang, Aoli;  Liu, Qingwang;  Deng, Maoqing;  Wang, Li;  Liu, Jing;  Liu, Qingsong
收藏  |  浏览/下载：40/0  |  提交时间：2022/12/23
CSF1R inhibitor  Kinase inhibitor  Macrophage polarization  
Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Wang, Zuo-wei;  Zou, Feng-ming;  Wang, Ao-li;  Yang, Jing;  Jin, Rui;  Wang, Bei-lei;  Shen, Li-juan;  Qi, Shuang;  Liu, Juan;  Liu, Jing;  Wang, Wen-chao;  Liu, Qing-song
收藏  |  浏览/下载：45/0  |  提交时间：2022/12/22
AZD4547  RIPK1  inhibitors  SIRS model  anti-necroptosis  
PEG-Bottlebrush Stabilizer-Based Worm-like Nanocrystal Micelles with Long-Circulating and Controlled Release for Delivery of a BCR-ABL Inhibitor against Chronic Myeloid Leukemia (CML) 期刊论文
PHARMACEUTICS, 2022, 卷号: 14
作者:  Liang, Huamin;  Zou, Fengming;  Fu, Liyi;  Liu, Qingwang;  Wang, Beilei;  Liang, Xiaofei;  Liu, Jing;  Liu, Qingsong
收藏  |  浏览/下载：48/0  |  提交时间：2022/12/23
drug nanocrystal  stabilizer  micelle  BCR-ABL  chronic myeloid leukemia (CML)  
CHMFL-26 is a highly potent irreversible HER2 inhibitor for use in the treatment of HER2-positive and HER2-mutant cancers 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Cao, Jiang-yan;  Qi, Shuang;  Wu, Hong;  Wang, Ao-li;  Liu, Qing-wang;  Li, Xi-xiang;  Wang, Bei-lei;  Ge, Juan;  Zou, Feng-ming;  Chen, Cheng;  Wang, Jun-jie;  Hu, Chen;  Liu, Jing;  Wang, Wen-chao;  Liu, Qing-song
收藏  |  浏览/下载：94/0  |  提交时间：2022/03/28
HER2  breast cancers  gastric cancers  irreversible inhibitor  drug resistance  
An overview of kinase downregulators and recent advances in discovery approaches 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
作者:  Wang, Beilei;  Wu, Hong;  Hu, Chen;  Wang, Haizhen;  Liu, Jing;  Wang, Wenchao;  Liu, Qingsong
收藏  |  浏览/下载：72/0  |  提交时间：2022/01/25
Targeting chaperon protein HSP70 as a novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
作者:  Hu, Chen;  Zou, Fengming;  Wang, Aoli;  Miao, Weili;  Liang, Qianmao;  Weisberg, Ellen L.;  Wang, Yinsheng;  Liu, Jing;  Wang, Wenchao;  Liu, Qingsong
收藏  |  浏览/下载：54/0  |  提交时间：2021/11/01
Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML) 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 897
作者:  Lu, Tingting;  Cao, Jiangyan;  Zou, Fengming;  Li, Xixiang;  Wang, Aoli;  Wang, Wenliang;  Liang, Huamin;  Liu, Qingwang;  Hu, Chen;  Chen, Cheng;  Hu, Zhenquan;  Wang, Wenchao;  Li, Lili;  Ge, Jian;  Shen, Yang;  Ren, Tao;  Liu, Jing;  Xia, Ruixiang;  Liu, Qingsong
收藏  |  浏览/下载：69/0  |  提交时间：2021/04/26
BCR-ABL  ABL mutants  Chronic myeloid leukemia  Kinase inhibitor  Imatinib resistance  
Nanocrystal-loaded liposome for targeted delivery of poorly water-soluble antitumor drugs with high drug loading and stability towards efficient cancer therapy 期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 卷号: 599
作者:  Liang, Huamin;  Zou, Fengming;  Liu, Qingwang;  Wang, Beilei;  Fu, Liyi;  Liang, Xiaofei;  Liu, Jing;  Liu, Qingsong
收藏  |  浏览/下载：48/0  |  提交时间：2021/05/17
Liposome  Drug nanocrystal  Core-shell  Drug delivery  Tumor therapy  BCR-ABL  
Selectively targeting FLT3-ITD mutants over FLT3-wt by a novel inhibitor for acute myeloid leukemia 期刊论文
HAEMATOLOGICA, 2021, 卷号: 106
作者:  Wang, Aoli;  Hu, Chen;  Chen, Cheng;  Liang, Xiaofei;  Wang, Beilei;  Zou, Fengming;  Yu, Kailin;  Li, Feng;  Liu, Qingwang;  Qi, Ziping;  Wang, Junjie;  Wang, Wenliang;  Wang, Li;  Weisberg, Ellen L.;  Wang, Wenchao;  Li, Lili;  Ge, Jian;  Xia, Ruixiang;  Liu, Jing;  Liu, Qingsong
收藏  |  浏览/下载：49/0  |  提交时间：2021/04/26
Discovery of a highly potent and selective Bruton's tyrosine kinase inhibitor avoiding impairment of ADCC effects for B-cell non-Hodgkin lymphoma 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5
作者:  Liu, Juan;  Liang, Qianmao;  Wang, Aoli;  Zou, Fengming;  Qi, Ziping;  Yu, Kailin;  Liu, Qingwang;  Chen, Cheng;  Liu, Jing;  Liu, Qingsong
收藏  |  浏览/下载：47/0  |  提交时间：2020/11/30