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HFCAS OpenIR

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Discovery of Pyrrolo[2,3-d]pyrimidine derivatives as potent and selective colony stimulating factor 1 receptor kinase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243
作者:  Liang, Xiaofei;  Wang, Chun;  Wang, Beilei;  Liu, Juan;  Qi, Shuang;  Wang, Aoli;  Liu, Qingwang;  Deng, Maoqing;  Wang, Li;  Liu, Jing;  Liu, Qingsong
收藏  |  浏览/下载：39/0  |  提交时间：2022/12/23
CSF1R inhibitor  Kinase inhibitor  Macrophage polarization  
Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Wang, Zuo-wei;  Zou, Feng-ming;  Wang, Ao-li;  Yang, Jing;  Jin, Rui;  Wang, Bei-lei;  Shen, Li-juan;  Qi, Shuang;  Liu, Juan;  Liu, Jing;  Wang, Wen-chao;  Liu, Qing-song
收藏  |  浏览/下载：45/0  |  提交时间：2022/12/22
AZD4547  RIPK1  inhibitors  SIRS model  anti-necroptosis  
Observation and simulation of HOx radicals in an urban area in Shanghai, China 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 卷号: 810
作者:  Zhang, Guoxian;  Hu, Renzhi;  Xie, Pinhua;  Lou, Shengrong;  Wang, Fengyang;  Wang, Yihui;  Qin, Min;  Li, Xin;  Liu, Xiaoyan;  Wang, Yue;  Liu, Wenqing
收藏  |  浏览/下载：77/0  |  提交时间：2022/02/14
FAGE-LIF  OH and HO2 radicals  ROx budget  Atmospheric oxidation  
CHMFL-26 is a highly potent irreversible HER2 inhibitor for use in the treatment of HER2-positive and HER2-mutant cancers 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Cao, Jiang-yan;  Qi, Shuang;  Wu, Hong;  Wang, Ao-li;  Liu, Qing-wang;  Li, Xi-xiang;  Wang, Bei-lei;  Ge, Juan;  Zou, Feng-ming;  Chen, Cheng;  Wang, Jun-jie;  Hu, Chen;  Liu, Jing;  Wang, Wen-chao;  Liu, Qing-song
收藏  |  浏览/下载：93/0  |  提交时间：2022/03/28
HER2  breast cancers  gastric cancers  irreversible inhibitor  drug resistance  
Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2 期刊论文
LEUKEMIA, 2022
作者:  Yang, Jing;  Weisberg, Ellen L.;  Qi, Shuang;  Ni, Wei;  Mei, Husheng;  Wang, Zuowei;  Meng, Chengcheng;  Zhang, Shengzhe;  Hou, Mingqi;  Qi, Ziping;  Wang, Aoli;  Jiang, Yunyun;  Jiang, Zongru;  Huang, Tao;  Liu, Qingwang;  Magin, Robert S.;  Doherty, Laura;  Wang, Wenchao;  Liu, Jing;  Buhrlage, Sara J.;  Liu, Qingsong;  Griffin, James D.
收藏  |  浏览/下载：76/0  |  提交时间：2022/02/14
An overview of kinase downregulators and recent advances in discovery approaches 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
作者:  Wang, Beilei;  Wu, Hong;  Hu, Chen;  Wang, Haizhen;  Liu, Jing;  Wang, Wenchao;  Liu, Qingsong
收藏  |  浏览/下载：71/0  |  提交时间：2022/01/25
Targeting chaperon protein HSP70 as a novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
作者:  Hu, Chen;  Zou, Fengming;  Wang, Aoli;  Miao, Weili;  Liang, Qianmao;  Weisberg, Ellen L.;  Wang, Yinsheng;  Liu, Jing;  Wang, Wenchao;  Liu, Qingsong
收藏  |  浏览/下载：54/0  |  提交时间：2021/11/01
Characteristic analysis of continuous new particle formation events in Hefei: A case study of the May Day holiday in China 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 卷号: 220
作者:  Ou, Jinping;  Hu, Qihou;  Liu, Haoran;  Hong, Qianqian;  Wang, Xinqi;  Xu, Shiqi;  Wang, Zhuang;  Liu, Wenqing
收藏  |  浏览/下载：50/0  |  提交时间：2021/08/31
Continuous NPF events  Health risk assessment  Regional transport  Hefei  PM2.5  
Vertical characterization and potential sources of aerosols in different seasons over the Yangtze River Delta using ground-based MAX-DOAS 期刊论文
ENVIRONMENTAL POLLUTION, 2021, 卷号: 279
作者:  Ou, Jinping;  Hu, Qihou;  Liu, Haoran;  Hong, Qianqian;  Xing, Chengzhi;  Tan, Wei;  Lin, Hua;  Wang, Xinqi;  Xu, Heng;  Zhu, Pengcheng;  Liu, Wenqing
收藏  |  浏览/下载：48/0  |  提交时间：2021/06/15
Multi-axis differential optical absorption spectroscopy (MAX-DOAS)  Hefei  Regional transport  Aerosol extinction coefficient  
Tunable and Passively Mode-Locking Nd-0.01:Gd0.89La0.1NbO4 Picosecond Laser 期刊论文
MOLECULES, 2021, 卷号: 26
作者:  Liu, Shande;  Zhao, Yuqing;  Zhang, Ke;  Chen, Bo;  Zhang, Ning;  Li, Dehua;  Zhang, Huiyun;  Zhang, Yuping;  Wang, Lihua;  Ding, Shoujun;  Zhang, Qingli
收藏  |  浏览/下载：68/0  |  提交时间：2021/08/31
Nd  GLNO crystal  tunable laser  mode-locking