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HFCAS OpenIR
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Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2 期刊论文
LEUKEMIA, 2022
作者:  Yang, Jing;  Weisberg, Ellen L.;  Qi, Shuang;  Ni, Wei;  Mei, Husheng;  Wang, Zuowei;  Meng, Chengcheng;  Zhang, Shengzhe;  Hou, Mingqi;  Qi, Ziping;  Wang, Aoli;  Jiang, Yunyun;  Jiang, Zongru;  Huang, Tao;  Liu, Qingwang;  Magin, Robert S.;  Doherty, Laura;  Wang, Wenchao;  Liu, Jing;  Buhrlage, Sara J.;  Liu, Qingsong;  Griffin, James D.
收藏  |  浏览/下载：76/0  |  提交时间：2022/02/14
Repurposing of Kinase Inhibitors for Treatment of COVID-19 期刊论文
PHARMACEUTICAL RESEARCH, 2020, 卷号: 37
作者:  Weisberg, Ellen;  Parent, Alexander;  Yang, Priscilla L.;  Sattler, Martin;  Liu, Qingsong;  Liu, Qingwang;  Wang, Jinhua;  Meng, Chengcheng;  Buhrlage, Sara J.;  Gray, Nathanael;  Griffin, James D.
收藏  |  浏览/下载：38/0  |  提交时间：2020/10/26
Coronavirus  SARS-CoV-2  SARS-CoV  MERS-CoV  kinase inhibitors  pharmacokinetics  antiviral therapy  COVID-19  
Simultaneous inhibition of Vps34 kinase would enhance PI3K delta inhibitor cytotoxicity in the B-cell malignancies 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 33, 页码: 53515-53525
作者:  Liu, Xiaochuan;  Wang, Aoli;  Liang, Xiaofei;  Liu, Juanjuan;  Zou, Fengming;  Chen, Cheng;  Zhao, Zheng;  Deng, Yuanxin;  Wu, Hong;  Qi, Ziping;  Wang, Beilei;  Wang, Li;  Liu, Feiyang;  Xu, Yunhe;  Wang, Wenchao;  Fernandes, Stacey M.;  Stone, Richard M.;  Galinsky, Ilene A.;  Brown, Jennifer R.;  Loh, Teckpeng;  Griffin, James. D.;  Zhang, Shanchun;  Weisberg, Ellen L.;  Zhang, Xin;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(7625Kb)  |  收藏  |  浏览/下载：95/37  |  提交时间：2017/11/21
Pi3k Delta  Vps34  Combination  Chronic Lymphatic Leukemia  Acute Myeloid Leukemia  
Characterization of selective and potent PI3K delta inhibitor (PI3KD-IN-015) for B-Cell malignances 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 22, 页码: 32641-32651
作者:  Liu, Xiaochuan;  Wang, Aoli;  Liang, Xiaofei;  Chen, Cheng;  Liu, Juanjuan;  Zhao, Zheng;  Wu, Hong;  Deng, Yuanxin;  Wang, Li;  Wang, Beilei;  Wu, Jiaxin;  Liu, Feiyang;  Fernandes, Stacey M.;  Adamia, Sophia;  Stone, Richard M.;  Galinsky, Ilene A.;  Brown, Jennifer R.;  Griffin, James D.;  Zhang, Shanchun;  Loh, Teckpeng;  Zhang, Xin;  Wang, Wenchao;  Weisberg, Ellen L.;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(5138Kb)  |  收藏  |  浏览/下载：80/28  |  提交时间：2017/11/16
Pi3k Delta  Leukemia  B-cell Malignances  Pi3k  Kinase Inhibitors  
Dual Inhibition of AKT/FLT3-ITD by A674563 Overcomes FLT3 Ligand-Induced Drug Resistance in FLT3-ITD positive AML 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 20, 页码: 29131-29142
作者:  Wang, Aoli;  Wu, Hong;  Chen, Cheng;  Hu, Chen;  Qi, Ziping;  Wang, Wenchao;  Yu, Kailin;  Liu, Xiaochuan;  Zou, Fengming;  Zhao, Zheng;  Wu, Jiaxin;  Liu, Juan;  Liu, Feiyang;  Wang, Li;  Stone, Richard M.;  Galinksy, Ilene A.;  Griffin, James D.;  Zhang, Shanchun;  Weisberg, Ellen L.;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(4786Kb)  |  收藏  |  浏览/下载：132/35  |  提交时间：2017/11/16
Acute Myeloid Leukemia  Flt3-itd  Akt  A6745763  Flt3-ligand  
Identification of Wee1 and IGF-1R As Novel Therapeutic Targets for Mutant RAS-Driven Acute Leukemia By Combinatory Chemical Screens 期刊论文
BLOOD, 2014, 卷号: 124, 期号: 21, 页码: 3
作者:  Nonami, Atsushi;  Zhao, Chen;  Liu Qingsong;  Cowens, Kristen;  Christie, Amanda L.;  Chen, Yongfei;  Sattler, Martin;  Wang, Kwok-Kin;  Gray, Nathanael S.;  Griffin, James D.;  Weisberg, Ellen L.
收藏  |  浏览/下载：39/0  |  提交时间：2019/06/03
Discovery of a Selective Irreversible BMX Inhibitor for Prostate Cancer 期刊论文
ACS CHEMICAL BIOLOGY, 2013, 卷号: 8, 期号: 7, 页码: 1423-1428
作者:  Liu, Feiyang;  Zhang, Xin;  Weisberg, Ellen;  Chen, Sen;  Hur, Wooyoung;  Wu, Hong;  Zhao, Zheng;  Wang, Wenchao;  Mao, Mao;  Cai, Changmeng;  Simon, Nicholas I.;  Sanda, Takaomi;  Wang, Jinhua;  Look, A. Thomas;  Griffin, James D.;  Balk, Steven P.;  Liu, Qingsong;  Gray, Nathanael S.
Adobe PDF(3259Kb)  |  收藏  |  浏览/下载：123/56  |  提交时间：2014/11/12