HFCAS OpenIR
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Ambient PM2.5 exposure causes cellular senescence via DNA damage, micronuclei formation, and cGAS activation 期刊论文
NANOTOXICOLOGY, 2022
作者:  Wu, Tao;  Xu, Shengmin;  Chen, Biao;  Bao, Lingzhi;  Ma, Jie;  Han, Wei;  Xu, An;  Yu, Kwan Ngok;  Wu, Lijun;  Chen, Shaopeng
收藏  |  浏览/下载:36/0  |  提交时间:2022/12/23
PM2  5  senescence  cGAS  micronuclei  DNA damage  
DNA damage-induced translocation of mitochondrial factor HIGD1A into the nucleus regulates homologous recombination and radio/chemo-sensitivity 期刊论文
ONCOGENE, 2022
作者:  Chen, Bin;  Xu, Feng;  Gao, Yang;  Hu, Guanshuo;  Zhu, Kaili;  Lu, Huayi;  Xu, An;  Chen, Shaopeng;  Wu, Lijun;  Zhao, Guoping
收藏  |  浏览/下载:59/0  |  提交时间:2022/03/21
Silver nanoparticles protect against arsenic induced genotoxicity via attenuating arsenic bioaccumulation and elevating antioxidation in mammalian cells 期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2021, 卷号: 413
作者:  Wang, Xue;  Nie, Yaguang;  Si, Bo;  Wang, Tong;  Hei, Tom K.;  Du, Hua;  Zhao, Guoping;  Chen, Shaopeng;  Xu, An;  Liu, Yun
收藏  |  浏览/下载:53/0  |  提交时间:2021/06/15
Arsenic (As)  Silver nanoparticles (AgNPs)  Detoxification  Bioaccumulation  Antioxidation  
Ecotoxicity Risk of Low-Dose Methylmercury Exposure to Caenorhabditis elegans: Multigenerational Toxicity and Population Discrepancy 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2021, 卷号: 34
作者:  Hu, Kunyu;  Xu, Yun;  Xu, Shengmin;  Cheng, Lei;  Zhou, Tong;  Xie, Aidi;  Xu, An;  Wu, Lijun;  Chen, Shaopeng
收藏  |  浏览/下载:51/0  |  提交时间:2021/06/15
Intratracheally instillated diesel PM2.5 significantly altered the structure and composition of indigenous murine gut microbiota 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 卷号: 210
作者:  Liu, Ying;  Wang, Tong;  Si, Bo;  Du, Hua;  Liu, Yun;  Waqas, Ahmed;  Huang, Shengwei;  Zhao, Guoping;  Chen, Shaopeng;  Xu, An
收藏  |  浏览/下载:53/0  |  提交时间:2021/04/26
Diesel PM2.5  Intratracheal instillation  Gut microbiota  Structure  Composition  
Monitoring arsenic using genetically encoded biosensors in vitro: The role of evolved regulatory genes 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 卷号: 207
作者:  Wang, Xuanyu;  Zhu, Kaili;  Chen, Dongdong;  Wang, Juan;  Wang, Xiaofei;  Xu, An;  Wu, Lijun;  Li, Luzhi;  Chen, Shaopeng
收藏  |  浏览/下载:46/0  |  提交时间:2020/12/28
Toxic pollutant  Genetically encoded biosensors  In vitro  Evolved regulatory genes  Arsenic  
Silver nanoparticle-activated COX2/PGE2 axis involves alteration of lung cellular senescence in vitro and in vivo 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 204
作者:  Chen, Biao;  Chai, Qing;  Xu, Shengmin;  Li, Qian;  Wu, Tao;  Chen, Shaopeng;  Wu, Lijun
收藏  |  浏览/下载:53/0  |  提交时间:2020/11/30
Silver nanoparticles  Lung cellular senescence  COX2  SASP  Human respiratory system  
Antagonizing CDK8 Sensitizes Colorectal Cancer to Radiation Through Potentiating the Transcription of e2f1 Target Gene apaf1 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, 卷号: 8
作者:  Chen, Bin;  Wen, Pengbo;  Hu, Guanshuo;  Gao, Yang;  Qi, Xiaojing;  Zhu, Kaili;  Chen, Shaopeng;  Wu, Lijun;  Xu, An;  Zhao, Guoping
收藏  |  浏览/下载:34/0  |  提交时间:2020/10/21
CDK8  transcriptional regulation  e2f1  apaf1  radiotherapy  apoptosis  
UV-induced over time transformation of AgNPs in commercial wound dressings and adverse biological effects on Caenorhabditis elegans 期刊论文
NANOIMPACT, 2020, 卷号: 17
作者:  Nie, Yaguang;  Wang, Jingjing;  Dai, Hui;  Wang, Juan;  Wang, Mudi;  Cheng, Lei;  Yang, Zhen;  Chen, Shaopeng;  Zhao, Guoping;  Wu, Lijun;  Xu, An
收藏  |  浏览/下载:51/0  |  提交时间:2020/11/26
released AgNPs  Physicochemical transformation  UV radiation  toxicity  Caenorhabditis elegans  
Transgenerational effects of diesel particulate matter on Caenorhabditis elegans through maternal and multigenerational exposure 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 170, 期号: 无, 页码: 635-643
作者:  Wang, Mudi;  Nie, Yaguang;  Liu, Ying;  Dai, Hui;  Wang, Jingjing;  Si, Bo;  Yang, Zhen;  Cheng, Lei;  Liu, Yun;  Chen, Shaopeng;  Xu, An
浏览  |  Adobe PDF(6386Kb)  |  收藏  |  浏览/下载:116/42  |  提交时间:2020/05/21
Diesel Particulate Matter  Caenorhabditis elegans  Multigenerational  Reproductive toxicity  Germ cell apoptosis