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Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
Authors:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen;  Wu, Hong;  Zhang, Yicong;  Liu, Xiaochuan;  Wang, Wenliang;  Wang, Junjie;  Hu, Zhenquan;  Wang, Aoli;  Huang, Tao;  Liu, Qingwang;  Wang, Wei;  Wang, Li;  Wang, Wenchao;  Ren, Tao;  Li, Lili;  Xia, Ruixiang;  Ge, Jian;  Liu, Qingsong;  Liu, Jing
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ABL kinase  Kinase inhibitor  ABL mutant  CML  
Czochralski growth and spectral investigations of Er:GSAG laser crystal 期刊论文
JOURNAL OF LUMINESCENCE, 2018, 卷号: 199, 页码: 60-66
Authors:  Chen, Yuanzhi;  Zhang, Qingli;  Peng, Fang;  Liu, Wenpeng;  Dou, Renqin;  He, Yi;  Sun, Guihua;  Cheng, Maojie;  Sun, Dunlu
Favorite  |  View/Download:2/0  |  Submit date:2019/08/23
Er:GSAG  Crystal growth  J-O theory  Laser  Fluorescence lifetime  
Scanning vertical distributions of typical aerosols along the Yangtze River using elastic lidar 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 卷号: 628-629, 期号: 无, 页码: 631-641
Authors:  Fan, Shidong;  Liu, Cheng;  Xie, Zhouqing;  Dong, Yunsheng;  Hu, Qihou;  Fan, Guangqiang;  Chen, Zhengyi;  Zhang, Tianshu;  Duan, Jingbo;  Zhang, Pengfei;  Liu, Jianguo
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Lidar  Vertical distribution  Dust aerosol  Biomass-burning aerosol  Secondary process  
Series Solution for Magnetic Flux Density of Circular Current Loop and a Relevant Application 期刊论文
JOURNAL OF FUSION ENERGY, 2018, 卷号: 37, 期号: 2-3, 页码: 130-135
Authors:  Guo, Yong-chao;  Zhang, Yan;  Cheng, Xiang-yu;  Huang, Peng-cheng;  Fang, Zhen;  Chen, Wen-ge
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Circular current  Magnetic flux density  Series solution  Application  
Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFR alpha kinase inhibitor for PDGFR alpha driving chronic eosinophilic leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 150, 期号: 无, 页码: 366-384
Authors:  Wang, Qiang;  Liu, Feiyang;  Qi, Shuang;  Qi, Ziping;  Yan, Xiao-E.;  Wang, Beilei;  Wang, Aoli;  Wang, Wei;  Chen, Cheng;  Liu, Xiaochuan;  Jiang, Zongru;  Hu, Zhenquan;  Wang, Li;  Wang, Wenchao;  Ren, Tao;  Zhang, Shanchun;  Yun, Cai-Hong;  Liu, Qingsong;  Liu, Jing
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PDGFR kinase  Type II inhibitor  Kinase inhibitor  CEL  
Recent ICRF coupling experiments on EAST 期刊论文
PLASMA SCIENCE & TECHNOLOGY, 2018, 卷号: 20, 期号: 4, 页码: 5
Authors:  Yang, Yuqing;  Zhang, Xinjun;  Zhao, Yanping;  Qin, Chengming;  Cheng, Yan;  Mao, Yuzhou;  Yang, Hua;  Wang, Jianhua;  Yuan, Shuai;  Wang, Lei;  Ju, Songqing;  Chen, Gen;  Deng, Xu;  Zhang, Kai;  Wan, Baonian;  Li, Jiangang;  Song, Yuntao;  Gong, Xianzu;  Qian, Jinping;  Zhang, Tao
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EAST  ICRF  antenna-plasma coupling  antenna phasing and gas puffing  
Design and test of voltage and current probes for EAST ICRF antenna impedance measurement 期刊论文
Plasma Science and Technology, 2018, 卷号: 20, 期号: 4, 页码: 1-6
Authors:  Wang JH(王健华);  Chen G(陈根);  Zhao YP(赵燕平);  Mao YZ(毛玉周);  Yuan S(袁帅);  Zhang XJ(张新军);  Yang H(杨桦);  Qin CM(秦成明);  Cheng Y(程艳);  Yang YQ(杨宇晴);  Guillaume URBANCZYK;  Liu LN(刘鲁南);  Cheng J(程健)
View  |  Adobe PDF(1722Kb)  |  Favorite  |  View/Download:31/7  |  Submit date:2018/10/29
ICRF antenna impedance measurements with voltage and current probes on EAST 期刊论文
FUSION ENGINEERING AND DESIGN, 2017, 卷号: 122, 期号: 无, 页码: 196-203
Authors:  Wang, J. H.;  Chen, G.;  Zhao, Y. P.;  Mao, Y. Z.;  Yuan, S.;  Zhang, X. J.;  Bernard, J. M.;  Lombard, G.;  Helou, W.;  Chen, Z.;  Urbanczyk, G.;  Qin, C. M.;  Cheng, Y.;  Yang, H.;  Zhang, J. H.;  Yang, Y. Q.;  Zhang, K.;  Ju, S. Q.;  Deng, X.;  Wan, B. N.;  Gong, X. Z.;  Li, J. G.;  Hu, L. Q.;  Song, Y. T.
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EAST  ICRF  Antenna impedance  Probe  Error  
Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders 期刊论文
JOURNAL OF EXPERIMENTAL MEDICINE, 2017, 卷号: 214, 期号: 11, 页码: 3219-3238
Authors:  Jiang, Hua;  He, Hongbin;  Chen, Yun;  Huang, Wei;  Cheng, Jinbo;  Ye, Jin;  Wang, Aoli;  Tao, Jinhui;  Wang, Chao;  Liu, Qingsong;  Jin, Tengchuan;  Jiang, Wei;  Deng, Xianming;  Zhou, Rongbin
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Discovery of 1-(4-(4-Amino-3-(4-(2-morpholinoethoxy)-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea (CHMFL-FLT3-213) as a Highly Potent Type II FLT3 Kinase Inhibitor Capable of Overcoming a Variety of FLT3 Kinase Mutants in FLT3-ITD Positive AML 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 20, 页码: 8407-8424
Authors:  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Wu, Hong;  Qi, Ziping;  Hu, Chen;  Yu, Kailin;  Wu, Jiaxin;  Liu, Juan;  Liu, Xiaochuan;  Hu, Zhenquan;  Wang, Wei;  Wang, Wenliang;  Wang, Wenchao;  Wang, Li;  Wang, Beilei;  Liu, Qingwang;  Li, Lili;  Ge, Jian;  Ren, Tao;  Zhang, Shanchun;  Xia, Ruixiang;  Liu, Jing;  Liu, Qingsong
View  |  Adobe PDF(10028Kb)  |  Favorite  |  View/Download:6/1  |  Submit date:2019/06/17