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Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML) 期刊论文
CANCER BIOLOGY & THERAPY, 2019, 卷号: 20, 期号: 6, 页码: 877-885
Authors:  Wu, Jiaxin;  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Qi, Ziping;  Hu, Chen;  Wang, Wenliang;  Wu, Hong;  Huang, Tao;  Zhao, Ming;  Wang, Wenchao;  Hu, Zhenquan;  Liu, Qingwang;  Wang, Beilei;  Wang, Li;  Li, Lili;  Ge, Jian;  Ren, Tao;  Xia, Ruixiang;  Liu, Jing
Favorite  |  View/Download:3/0  |  Submit date:2019/11/27
BCR-ABL  PDGFR  chronic myeloid leukemia  kinase inhibitor  
Improvement of Cr (VI) photoreduction under visible-light by g-C3N4 modified by nano-network structured palygorskite 期刊论文
CHEMICAL ENGINEERING JOURNAL, 2019, 卷号: 358, 页码: 398-407
Authors:  Zhang, Jing;  Gao, Ning;  Chen, Fulong;  Zhang, Tao;  Zhang, Guilong;  Wang, Dongfang;  Xie, Xingyong;  Cai, Dongqing;  Ma, Xijun;  Wu, Lifang;  Wu, Zhengyan
Adobe PDF(2784Kb)  |  Favorite  |  View/Download:43/7  |  Submit date:2019/01/09
Palygorskite  Graphitic carbon nitride  Ion beam bombardment  Photocatalysts  
Fabrication of Ag-nanosheet-assembled hollow tubular array and their SERS effect 期刊论文
JOURNAL OF ALLOYS AND COMPOUNDS, 2019, 卷号: 772, 页码: 663-668
Authors:  Zhang, Haibao;  Wang, Jingjing;  Li, Guang;  Chen, Lin;  Wang, Hua;  Tian, Xingyou
Adobe PDF(1386Kb)  |  Favorite  |  View/Download:31/9  |  Submit date:2019/01/09
Hollow tubular array  Electrodeposition  ZnO nanorods  SERS effect  
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
Authors:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen;  Wu, Hong;  Zhang, Yicong;  Liu, Xiaochuan;  Wang, Wenliang;  Wang, Junjie;  Hu, Zhenquan;  Wang, Aoli;  Huang, Tao;  Liu, Qingwang;  Wang, Wei;  Wang, Li;  Wang, Wenchao;  Ren, Tao;  Li, Lili;  Xia, Ruixiang;  Ge, Jian;  Liu, Qingsong;  Liu, Jing
Adobe PDF(4593Kb)  |  Favorite  |  View/Download:52/18  |  Submit date:2019/01/11
ABL kinase  Kinase inhibitor  ABL mutant  CML  
Estimation of carbon impurity from the guard limiter of the lower hybrid wave antenna on EAST tokamak 期刊论文
PLASMA PHYSICS AND CONTROLLED FUSION, 2018, 卷号: 60, 期号: 12, 页码: 11
Authors:  Ou, Jing;  Xiang, Nong;  Liu, Liang;  Men, Zongzheng;  Zhang, Ling;  Mao, Songtao;  Chen, Meiwen
Adobe PDF(1532Kb)  |  Favorite  |  View/Download:32/13  |  Submit date:2019/01/11
physical sputtering  chemical erosion  hot spot  plasma sheath  
Strategy Design and Transient Analysis of ITER PPEN Transformer On-Load Tap Changer During Converter Operation 期刊论文
JOURNAL OF FUSION ENERGY, 2018, 卷号: 37, 期号: 6, 页码: 346-353
Authors:  Fan, Renjing;  Fu, Peng;  Tao, Jun;  Gao, Ge;  Song, Zhiquan;  Huang, Liansheng;  Chen, Xiaojiao;  Li, Jinchao
Favorite  |  View/Download:0/0  |  Submit date:2019/12/25
ITER  Coil power supply  OLTC control  Hysteresis band  Converter operation robustness  
Refreshing Piezoelectrics: Distinctive Role of Manganese in Lead Free Perovskites 期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2018, 卷号: 10, 期号: 43, 页码: 37298-37306
Authors:  Yao, Fang-Zhou;  Zhang, Mao-Hua;  Wang, Ke;  Zhou, Jia-Jun;  Chen, Feng;  Xu, Bin;  Li, Fei;  Shen, Yang;  Zhang, Qing-Hua;  Gu, Lin;  Zhang, Xiao-Wen;  Li, Jing-Feng
Adobe PDF(2258Kb)  |  Favorite  |  View/Download:24/8  |  Submit date:2019/01/09
(K,Na)NbO3  lead free  perovskite  piezoelectric  manganese doping  
TiO2 nanoparticles enhance bioaccumulation and toxicity of heavy metals in Caenorhabditis elegans via modification of local concentrations during the sedimentation process 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2018, 卷号: 162, 页码: 160-169
Authors:  Wang, Jingjing;  Dai, Hui;  Nie, Yaguang;  Wang, Mudi;  Yang, Zhen;  Cheng, Lei;  Liu, Yun;  Chen, Shaopeng;  Zhao, Guoping;  Wu, Lijun;  Guang, Shouhong;  Xu, An
Favorite  |  View/Download:0/0  |  Submit date:2019/11/11
TiO2 nanoparticles  Heavy metals  Bioaccumulation  Toxicity  Caenorhabditis elegans  Sedimentation process  
Mechanisms involved in the impact of engineered nanomaterials on the joint toxicity with environmental pollutants 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2018, 卷号: 162, 页码: 92-102
Authors:  Liu, Yun;  Nie, Yaguang;  Wang, Jingjing;  Wang, Juan;  Wang, Xue;  Chen, Shaopeng;  Zhao, Guoping;  Wu, Lijun;  Xu, An
Favorite  |  View/Download:0/0  |  Submit date:2019/11/11
Nanomaterials  Pollutants  Joint toxicity  Synergistic effects  Antagonistic effects  Co-exposure  
Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 896-916
Authors:  Wang, Beilei;  Wu, Jiaxin;  Wu, Yun;  Chen, Cheng;  Zou, Fengming;  Wang, Aoli;  Wu, Hong;  Hu, Zhenquan;  Jiang, Zongru;  Liu, Qingwang;  Wang, Wei;  Zhang, Yicong;  Liu, Feiyang;  Zhao, Ming;  Hu, Jie;  Huang, Tao;  Ge, Juan;  Wang, Li;  Ren, Tao;  Wang, Yuxin;  Liu, Jing;  Liu, Qingsong
Favorite  |  View/Download:0/0  |  Submit date:2019/12/25
CDK9  Kinase inhibitor  Structure-activity relationship  Leukemia