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Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML) 期刊论文
CANCER BIOLOGY & THERAPY, 2019, 卷号: 20, 期号: 6, 页码: 877-885
Authors:  Wu, Jiaxin;  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Qi, Ziping;  Hu, Chen;  Wang, Wenliang;  Wu, Hong;  Huang, Tao;  Zhao, Ming;  Wang, Wenchao;  Hu, Zhenquan;  Liu, Qingwang;  Wang, Beilei;  Wang, Li;  Li, Lili;  Ge, Jian;  Ren, Tao;  Xia, Ruixiang;  Liu, Jing
Favorite  |  View/Download:3/0  |  Submit date:2019/11/27
BCR-ABL  PDGFR  chronic myeloid leukemia  kinase inhibitor  
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
Authors:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen;  Wu, Hong;  Zhang, Yicong;  Liu, Xiaochuan;  Wang, Wenliang;  Wang, Junjie;  Hu, Zhenquan;  Wang, Aoli;  Huang, Tao;  Liu, Qingwang;  Wang, Wei;  Wang, Li;  Wang, Wenchao;  Ren, Tao;  Li, Lili;  Xia, Ruixiang;  Ge, Jian;  Liu, Qingsong;  Liu, Jing
Adobe PDF(4593Kb)  |  Favorite  |  View/Download:55/20  |  Submit date:2019/01/11
ABL kinase  Kinase inhibitor  ABL mutant  CML  
Strategy Design and Transient Analysis of ITER PPEN Transformer On-Load Tap Changer During Converter Operation 期刊论文
JOURNAL OF FUSION ENERGY, 2018, 卷号: 37, 期号: 6, 页码: 346-353
Authors:  Fan, Renjing;  Fu, Peng;  Tao, Jun;  Gao, Ge;  Song, Zhiquan;  Huang, Liansheng;  Chen, Xiaojiao;  Li, Jinchao
Favorite  |  View/Download:0/0  |  Submit date:2019/12/25
ITER  Coil power supply  OLTC control  Hysteresis band  Converter operation robustness  
EDTA-Fe(III) Fenton-like oxidation for the degradation of malachite green 期刊论文
JOURNAL OF ENVIRONMENTAL MANAGEMENT, 2018, 卷号: 226, 页码: 256-263
Authors:  Hu, Yi;  Li, Yulian;  He, Junyong;  Liu, Tao;  Zhang, Kaisheng;  Huang, Xingjiu;  Kong, Lingtao;  Liu, Jinhuai
Favorite  |  View/Download:1/0  |  Submit date:2019/12/25
Fenton  EDTA  Malachite green  Degradation  Kinetics  Mechanism  
Full-inorganic Sb-2(S, Se)(3) solar cells using carbon as both hole selection material and electrode 期刊论文
ELECTROCHIMICA ACTA, 2018, 卷号: 290, 页码: 457-464
Authors:  Wang, Weihuang;  Chen, Guilin;  Wang, Zhezhe;  Wang, Ke;  Chen, Shuiyuan;  Huang, Zhigao;  Wang, Xiaomin;  Chen, Tao;  Zhu, Changfei;  Kong, Xiangkai
Favorite  |  View/Download:1/0  |  Submit date:2019/12/25
Sb-2(S,Se)(3)  Full-inorganic  Selenization  Solar cell  Carbon  
Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 896-916
Authors:  Wang, Beilei;  Wu, Jiaxin;  Wu, Yun;  Chen, Cheng;  Zou, Fengming;  Wang, Aoli;  Wu, Hong;  Hu, Zhenquan;  Jiang, Zongru;  Liu, Qingwang;  Wang, Wei;  Zhang, Yicong;  Liu, Feiyang;  Zhao, Ming;  Hu, Jie;  Huang, Tao;  Ge, Juan;  Wang, Li;  Ren, Tao;  Wang, Yuxin;  Liu, Jing;  Liu, Qingsong
Favorite  |  View/Download:2/0  |  Submit date:2019/12/25
CDK9  Kinase inhibitor  Structure-activity relationship  Leukemia  
Selenite Reduction and the Biogenesis of Selenium Nanoparticles by Alcaligenes faecalis Se03 Isolated from the Gut of Monochamus alternatus (Coleoptera: Cerambycidae) 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 9, 页码: 18
Authors:  Wang, Yuting;  Shu, Xian;  Zhou, Qing;  Fan, Tao;  Wang, Taichu;  Chen, Xue;  Li, Minghao;  Ma, Yuhan;  Ni, Jun;  Hou, Jinyan;  Zhao, Weiwei;  Li, Ruixue;  Huang, Shengwei;  Wu, Lifang
Adobe PDF(3060Kb)  |  Favorite  |  View/Download:18/1  |  Submit date:2019/01/11
selenite reduction  Alcaligenes faecalis  biogenic seleniumnanoparticles  electronmicroscopy analysis  real-time PCR  
Single atom accelerates ammonia photosynthesis 期刊论文
SCIENCE CHINA-CHEMISTRY, 2018, 卷号: 61, 期号: 9, 页码: 1187-1196
Authors:  Huang, Pengcheng;  Liu, Wei;  He, Zhihai;  Xiao, Chong;  Yao, Tao;  Zou, Youming;  Wang, Chengming;  Qi, Zeming;  Tong, Wei;  Pan, Bicai;  Wei, Shiqiang;  Xie, Yi
Favorite  |  View/Download:2/0  |  Submit date:2019/12/25
single atom  photocatalytic  ammonia synthesis  
Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders 期刊论文
JOURNAL OF EXPERIMENTAL MEDICINE, 2017, 卷号: 214, 期号: 11, 页码: 3219-3238
Authors:  Jiang, Hua;  He, Hongbin;  Chen, Yun;  Huang, Wei;  Cheng, Jinbo;  Ye, Jin;  Wang, Aoli;  Tao, Jinhui;  Wang, Chao;  Liu, Qingsong;  Jin, Tengchuan;  Jiang, Wei;  Deng, Xianming;  Zhou, Rongbin
View  |  Adobe PDF(2740Kb)  |  Favorite  |  View/Download:35/14  |  Submit date:2019/06/17
Fatigue performance evaluation for ITER IVC conductor component materials 期刊论文
VACUUM, 2017, 卷号: 145, 期号: 无, 页码: 86-94
Authors:  Jin, H.;  Vostner, A.;  Wu, Y.;  Macioce, D.;  Sgobba, S.;  Huang, C.;  Romero Rodriguez, C.;  Fernandez Pison, P.;  Langeslag, S. A. Elisabeth;  Aviles Santillana, I.;  Long, F.;  Yu, M.;  Tao, B.
Adobe PDF(1Kb)  |  Favorite  |  View/Download:14/2  |  Submit date:2019/02/28
OFE conductor  SS316LN  Cold working  Aging  S-N curve