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CHMFL-26 is a highly potent irreversible HER2 inhibitor for use in the treatment of HER2-positive and HER2-mutant cancers 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
Authors:  Cao, Jiang-yan;  Qi, Shuang;  Wu, Hong;  Wang, Ao-li;  Liu, Qing-wang;  Li, Xi-xiang;  Wang, Bei-lei;  Ge, Juan;  Zou, Feng-ming;  Chen, Cheng;  Wang, Jun-jie;  Hu, Chen;  Liu, Jing;  Wang, Wen-chao;  Liu, Qing-song
Favorite  |  View/Download:24/0  |  Submit date:2022/03/28
HER2  breast cancers  gastric cancers  irreversible inhibitor  drug resistance  
Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2 期刊论文
LEUKEMIA, 2022
Authors:  Yang, Jing;  Weisberg, Ellen L.;  Qi, Shuang;  Ni, Wei;  Mei, Husheng;  Wang, Zuowei;  Meng, Chengcheng;  Zhang, Shengzhe;  Hou, Mingqi;  Qi, Ziping;  Wang, Aoli;  Jiang, Yunyun;  Jiang, Zongru;  Huang, Tao;  Liu, Qingwang;  Magin, Robert S.;  Doherty, Laura;  Wang, Wenchao;  Liu, Jing;  Buhrlage, Sara J.;  Liu, Qingsong;  Griffin, James D.
Favorite  |  View/Download:25/0  |  Submit date:2022/02/14
An overview of kinase downregulators and recent advances in discovery approaches 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
Authors:  Wang, Beilei;  Wu, Hong;  Hu, Chen;  Wang, Haizhen;  Liu, Jing;  Wang, Wenchao;  Liu, Qingsong
Favorite  |  View/Download:16/0  |  Submit date:2022/01/25
Iodine cation bridged graphene sheets with strengthened interface combination for electromagnetic wave absorption 期刊论文
CARBON, 2021, 卷号: 183
Authors:  Li, Qingsong;  Li, Shitong;  Liu, Qiangchun;  Liu, Xiaofang;  Shui, Jianglan;  Kong, Xiangkai
Favorite  |  View/Download:6/0  |  Submit date:2021/11/15
Iodine cation  Microwave absorbing  Graphene  
Targeting chaperon protein HSP70 as a novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
Authors:  Hu, Chen;  Zou, Fengming;  Wang, Aoli;  Miao, Weili;  Liang, Qianmao;  Weisberg, Ellen L.;  Wang, Yinsheng;  Liu, Jing;  Wang, Wenchao;  Liu, Qingsong
Favorite  |  View/Download:5/0  |  Submit date:2021/11/01
Nanocrystal-loaded liposome for targeted delivery of poorly water-soluble antitumor drugs with high drug loading and stability towards efficient cancer therapy 期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 卷号: 599
Authors:  Liang, Huamin;  Zou, Fengming;  Liu, Qingwang;  Wang, Beilei;  Fu, Liyi;  Liang, Xiaofei;  Liu, Jing;  Liu, Qingsong
Favorite  |  View/Download:6/0  |  Submit date:2021/05/17
Liposome  Drug nanocrystal  Core-shell  Drug delivery  Tumor therapy  BCR-ABL  
Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML) 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 897
Authors:  Lu, Tingting;  Cao, Jiangyan;  Zou, Fengming;  Li, Xixiang;  Wang, Aoli;  Wang, Wenliang;  Liang, Huamin;  Liu, Qingwang;  Hu, Chen;  Chen, Cheng;  Hu, Zhenquan;  Wang, Wenchao;  Li, Lili;  Ge, Jian;  Shen, Yang;  Ren, Tao;  Liu, Jing;  Xia, Ruixiang;  Liu, Qingsong
Favorite  |  View/Download:11/0  |  Submit date:2021/04/26
BCR-ABL  ABL mutants  Chronic myeloid leukemia  Kinase inhibitor  Imatinib resistance  
Selectively targeting FLT3-ITD mutants over FLT3-wt by a novel inhibitor for acute myeloid leukemia 期刊论文
HAEMATOLOGICA, 2021, 卷号: 106
Authors:  Wang, Aoli;  Hu, Chen;  Chen, Cheng;  Liang, Xiaofei;  Wang, Beilei;  Zou, Fengming;  Yu, Kailin;  Li, Feng;  Liu, Qingwang;  Qi, Ziping;  Wang, Junjie;  Wang, Wenliang;  Wang, Li;  Weisberg, Ellen L.;  Wang, Wenchao;  Li, Lili;  Ge, Jian;  Xia, Ruixiang;  Liu, Jing;  Liu, Qingsong
Favorite  |  View/Download:8/0  |  Submit date:2021/04/26
Dynamic folding modulation generates FGF21 variant against diabetes 期刊论文
EMBO REPORTS, 2021, 卷号: 22
Authors:  Zhu, Lei;  Zhao, Hongxin;  Liu, Juanjuan;  Cai, Hao;  Wu, Bo;  Liu, Zhijun;  Zhou, Shu;  Liu, Qingsong;  Li, Xiaokun;  Bao, Bin;  Liu, Jian;  Dai, Han;  Wang, Junfeng
Favorite  |  View/Download:3/0  |  Submit date:2021/08/30
anti‐  diabetes  disulfide bond mutation  FGF21  folding dynamics  NMR  
Activating microwave absorption performance by reduced graphene oxide-borophene heterostructure 期刊论文
COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING, 2020, 卷号: 138
Authors:  Wang, Shipeng;  Li, Qingsong;  Hu, Kang;  Liu, Qiangchun;  Liu, Xiaofang;  Kong, Xiangkai
Favorite  |  View/Download:5/0  |  Submit date:2020/11/30
Graphene  Borophene  Metal-free  Microwave absorption