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Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML) 期刊论文
CANCER BIOLOGY & THERAPY, 2019, 卷号: 20, 期号: 6, 页码: 877-885
Authors:  Wu, Jiaxin;  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Qi, Ziping;  Hu, Chen;  Wang, Wenliang;  Wu, Hong;  Huang, Tao;  Zhao, Ming;  Wang, Wenchao;  Hu, Zhenquan;  Liu, Qingwang;  Wang, Beilei;  Wang, Li;  Li, Lili;  Ge, Jian;  Ren, Tao;  Xia, Ruixiang;  Liu, Jing
Favorite  |  View/Download:4/0  |  Submit date:2019/11/27
BCR-ABL  PDGFR  chronic myeloid leukemia  kinase inhibitor  
Photo-enhanced gas sensing of SnS2 with nanoscale defects 期刊论文
RSC ADVANCES, 2019, 卷号: 9, 期号: 2, 页码: 626-635
Authors:  Yan, Wen-Jie;  Chen, Deng-Yun;  Fuh, Huei-Ru;  Li, Ying-Lan;  Zhang, Duan;  Liu, Huajun;  Wu, Gang;  Zhang, Lei;  Ren, Xiangkui;  Cho, Jiung;  Choi, Miri;  Chun, Byong Sun;  Coileain, Cormac O.;  Xu, Hong-Jun;  Wang, Zhi;  Jiang, Zhaotan;  Chang, Ching-Ray;  Wu, Han-Chun
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Effect of heat treatment processing on microstructure and tensile properties of Ti-6Al-4V-10Nb alloy 期刊论文
TRANSACTIONS OF NONFERROUS METALS SOCIETY OF CHINA, 2019, 卷号: 29, 期号: 1, 页码: 59-66
Authors:  Sun, Hong;  Yu, Li-ming;  Liu, Yong-chang;  Zhang, Li-ye;  Liu, Chen-xi;  Li, Hui-jun;  Wu, Jie-feng
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Ti-6Al-4V-10Nb alloy  heat treatment  microstructure  primary alpha phase  secondary alpha phase  strength  
The distinct clinicopathological and prognostic implications of PIK3CA mutations in breast cancer patients from Central China 期刊论文
CANCER MANAGEMENT AND RESEARCH, 2019, 卷号: 11, 期号: 无, 页码: 1473-1492
Authors:  Wu, Haibo;  Wang, Wei;  Du, Jun;  Li, Hong;  Wang, Huogang;  Huang, Liangliang;  Xiang, Hang;  Xie, Jing;  Liu, Xiaoli;  Li, Heng;  Lin, Wenchu
View  |  Adobe PDF(1845Kb)  |  Favorite  |  View/Download:3/0  |  Submit date:2020/05/21
breast cancer  PIK3CA  clinicopathological characteristics  prognosis  
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
Authors:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen;  Wu, Hong;  Zhang, Yicong;  Liu, Xiaochuan;  Wang, Wenliang;  Wang, Junjie;  Hu, Zhenquan;  Wang, Aoli;  Huang, Tao;  Liu, Qingwang;  Wang, Wei;  Wang, Li;  Wang, Wenchao;  Ren, Tao;  Li, Lili;  Xia, Ruixiang;  Ge, Jian;  Liu, Qingsong;  Liu, Jing
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ABL kinase  Kinase inhibitor  ABL mutant  CML  
Pulsed axial epitaxy of colloidal quantum dots in nanowires enables facet-selective passivation 期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9, 页码: 8
Authors:  Li, Yi;  Zhuang, Tao-Tao;  Fan, Fengjia;  Voznyy, Oleksandr;  Askerka, Mikhail;  Zhu, Haiming;  Wu, Liang;  Liu, Guo-Qiang;  Pan, Yun-Xiang;  Sargent, Edward H.;  Yu, Shu-Hong
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Salviachinensines A-F, Antiproliferative Phenolic Derivatives from the Chinese Medicinal Plant Salvia chinensis 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2018, 卷号: 81, 期号: 11, 页码: 2531-2538
Authors:  Wang, Qi;  Hu, Zhenquan;  Li, Xixiang;  Wang, Aoli;  Wu, Hong;  Liu, Jing;  Cao, Shugeng;  Liu, Qingsong
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Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 896-916
Authors:  Wang, Beilei;  Wu, Jiaxin;  Wu, Yun;  Chen, Cheng;  Zou, Fengming;  Wang, Aoli;  Wu, Hong;  Hu, Zhenquan;  Jiang, Zongru;  Liu, Qingwang;  Wang, Wei;  Zhang, Yicong;  Liu, Feiyang;  Zhao, Ming;  Hu, Jie;  Huang, Tao;  Ge, Juan;  Wang, Li;  Ren, Tao;  Wang, Yuxin;  Liu, Jing;  Liu, Qingsong
Favorite  |  View/Download:2/0  |  Submit date:2019/12/25
CDK9  Kinase inhibitor  Structure-activity relationship  Leukemia  
Biomimetic twisted plywood structural materials 期刊论文
NATIONAL SCIENCE REVIEW, 2018, 卷号: 5, 期号: 5, 页码: 703-714
Authors:  Chen, Si-Ming;  Gao, Huai-Ling;  Zhu, Yin-Bo;  Yao, Hong-Bin;  Mao, Li-Bo;  Song, Qi-Yun;  Xia, Jun;  Pan, Zhao;  He, Zhen;  Wu, Heng-An;  Yu, Shu-Hong
Favorite  |  View/Download:8/0  |  Submit date:2019/12/25
biomimetic designs  micro/nanoscale building blocks  twisted plywood structures  damage tolerance  biomimetic bulk materials  toughening mechanisms  
SiO2-protected shell mediated templating synthesis of Fe-N-doped carbon nanofibers and their enhanced oxygen reduction reaction performance 期刊论文
ENERGY & ENVIRONMENTAL SCIENCE, 2018, 卷号: 11, 期号: 8, 页码: 2208-2215
Authors:  Hu, Bi-Cheng;  Wu, Zhen-Yu;  Chu, Sheng-Qi;  Zhu, Hong-Wu;  Liang, Hai-Wei;  Zhang, Jing;  Yu, Shu-Hong
Favorite  |  View/Download:1/0  |  Submit date:2019/11/11