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Chinese expert consensus on the multidisciplinary management of pneumonitis associated with immune checkpoint inhibitor 期刊论文
THORACIC CANCER, 2022
作者:  Wang, Wenxian;  Wang, Qian;  Xu, Chunwei;  Li, Ziming;  Song, Zhengbo;  Zhang, Yongchang;  Cai, Xiuyu;  Zhang, Shirong;  Lian, Bin;  Li, Wen;  Liu, Anwen;  Zhan, Ping;  Liu, Hongbing;  Lv, Tangfeng;  Miao, Liyun;  Min, Lingfeng;  Chen, Yu;  Yuan, Jingping;  Wang, Feng;  Jiang, Zhansheng;  Lin, Gen;  Pu, Xingxiang;  Rao, Chuangzhou;  Lv, Dongqing;  Yu, Zongyang;  Li, Xiaoyan;  Tang, Chuanhao;  Zhou, Chengzhi;  Xie, Congying;  Zhang, Junping;  Guo, Hui;  Chu, Qian;  Meng, Rui;  Wu, Jingxun;  Zhang, Rui;  Wang, Liping;  Zhu, Youcai;  Hu, Xiao;  Xie, Yanru;  Lin, Xinqing;  Cai, Jing;  Lan, Fen;  Feng, Huijing;  Wang, Lin;  Yao, Wang;  Shi, Xuefei;  Huang, Jianhui;  Chen, Huafei;  Zhang, Yinbin;  Sun, Pingli;  Wan, Bing;  Pang, Fei;  Xu, Zanmei;  Wang, Kai;  Xia, Yuanli;  Ye, Mingxiang;  Wang, Dong;  Wei, Qing;  Feng, Shuitu;  Zhou, Jianya;  Zhang, Jiexia;  Lv, Donglai;  Gao, Wenbin;  Kang, Jing;  Yu, Genhua;  Liang, Xianbin;  Yu, Chengtao;  Shi, Lin;  Yang, Nong;  Wu, Lin;  Hong, Zhuan;  Hong, Wei;  Fang, Meiyu;  Zhang, Yiping;  Lu, Yuanzhi;  Wang, Guansong;  Ma, Shenglin;  Si, Lu;  Fang, Wenfeng;  Song, Yong
收藏  |  浏览/下载：43/0  |  提交时间：2022/12/23
checkpoint inhibitor pneumonitis  Chinese experts consensus  immune checkpoint inhibitor-related adverse effects  
Engineering design of the CFETR machine 期刊论文
FUSION ENGINEERING AND DESIGN, 2022, 卷号: 183
作者:  Song, Yuntao;  Li, Jiangang;  Wan, Yuanxi;  Liu, Yong;  Wang, Xiaolin;  Wan, Baonian;  Fu, Peng;  Weng, Peide;  Wu, Songtao;  Duan, Xuru;  Yang, Qingwei;  Feng, Kaiming;  Li, Qiang;  Ye, Mingyou;  Zhuang, Ge;  Liang, Yunfeng;  Gao, Xiang;  Chen, Changan;  Wang, Heyi;  Zheng, Guoyao;  Xu, Yuhong;  Qian, Tianlin;  Chan, Vincent;  Xiao, Bingjia;  Lu, Kun;  Zheng, Jinxing;  Lu, Mingxuan;  Liu, Dequan;  Liu, Jian;  Wu, Yu;  Liu, Xufeng;  Shi, Yi;  Hou, Binglin;  Liu, Chen;  Ge, Jian;  Zhou, Caipin;  Ran, Hong;  Wang, Qijie;  Wang, Xiaoyu;  Liu, Songlin;  Liu, Sumei;  Yao, Damao;  Cheng, Yong;  Hu, Liqun;  Hu, Chundong;  Liu, Fukun;  Chen, Gen
收藏  |  浏览/下载：45/0  |  提交时间：2022/12/22
CFETR  Engineering design  Tokamak  Magnetic confinement  
Expert consensus on the diagnosis and treatment of NTRK gene fusion solid tumors in China 期刊论文
THORACIC CANCER, 2022
作者:  Xu, Chunwei;  Si, Lu;  Wang, Wenxian;  Li, Ziming;  Song, Zhengbo;  Wang, Qian;  Liu, Aijun;  Yu, Jinpu;  Fang, Wenfeng;  Zhong, Wenzhao;  Wang, Zhijie;  Zhang, Yongchang;  Liu, Jingjing;  Zhang, Shirong;  Cai, Xiuyu;  Liu, Anwen;  Li, Wen;  Zhan, Ping;  Liu, Hongbing;  Lv, Tangfeng;  Miao, Liyun;  Min, Lingfeng;  Chen, Yu;  Yuan, Jingping;  Wang, Feng;  Jiang, Zhansheng;  Lin, Gen;  Pu, Xingxiang;  Lin, Rongbo;  Liu, Weifeng;  Rao, Chuangzhou;  Lv, Dongqing;  Yu, Zongyang;  Lei, Lei;  Li, Xiaoyan;  Tang, Chuanhao;  Zhou, Chengzhi;  Zhang, Junping;  Xue, Junli;  Guo, Hui;  Chu, Qian;  Meng, Rui;  Wu, Jingxun;  Zhang, Rui;  Hu, Xiao;  Zhou, Jin;  Zhu, Zhengfei;  Li, Yongheng;  Qiu, Hong;  Xia, Fan;  Lu, Yuanyuan;  Chen, Xiaofeng;  Ge, Rui;  Dai, Enyong;  Han, Yu;  Pan, Weiwei;  Luo, Jiancheng;  Jia, Hongtao;  Dong, Xiaowei;  Pang, Fei;  Wang, Kai;  Wang, Liping;  Zhu, Youcai;  Xie, Yanru;  Lin, Xinqin;  Cai, Jing;  Wei, Jia;  Lan, Fen;  Feng, Huijing;  Wang, Lin;  Du, Yingying;  Yao, Wang;  Shi, Xuefei;  Niu, Xiaomin;  Yuan, Dongmei;  Yao, Yanwen;  Huang, Jianhui;  Zhang, Yinbin;  Sun, Pingli;  Wang, Hong;  Ye, Mingxiang;  Wang, Dong;  Wang, Zhaofeng;  Wan, Bing;  Lv, Donglai;  Wei, Qing;  Kang, Jin;  Zhang, Jiatao;  Zhang, Chao;  Yu, Genhua;  Ou, Juanjuan;  Shi, Lin;  Li, Zhongwu;  Liu, Zhefeng;  Liu, Jing;  Yang, Nong;  Wu, Lin;  Wang, Huijuan;  Jin, Gu;  Yang, Liu;  Wang, Guansong;  Fang, Meiyu;  Fang, Yong;  Li, Yuan;  Wang, Xiaojia;  Zhang, Yiping;  Ma, Shenglin;  Wang, Biyun;  Zhang, Xiaotian;  Song, Yong;  Lu, Yuanzhi
收藏  |  浏览/下载：42/0  |  提交时间：2022/12/22
fusion  precision medicine  solid tumor  targeted therapy  tyrosine receptor kinase  
Laboratory Calibration of an Ultraviolet-Visible Imaging Spectropolarimeter 期刊论文
REMOTE SENSING, 2022, 卷号: 14
作者:  Shi, Jingjing;  Li, Mengfan;  Hu, Yadong;  Wang, Xiangjing;  Xu, Hua;  Chi, Gaojun;  Hong, Jin
收藏  |  浏览/下载：33/0  |  提交时间：2022/12/23
spectropolarimeter  polarization  geometric calibration  spectral calibration  radiometric calibration  polarimetric calibration  

KrF excimer laser induced damage and its mechanism of CaF2 single crystal with (111), (110) and (100) planes

 期刊论文
APPLIED SURFACE SCIENCE, 2022, 卷号: 586
作者:  Shao, Jingzhen;  Liang, Xu;  Lin, Ying;  Wang, Shimao;  Deng, Zanhong;  Meng, Gang;  Fang, Xiaodong
收藏  |  浏览/下载：58/0  |  提交时间：2022/05/16
Excimer lasers  Laser damage  Calcium fluoride  Crystal structures  
Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235
作者:  Qu, Bingxue;  Xu, Yongjin;  Lu, Yang;  Zhuang, Weihao;  Jin, Xinxin;  Shi, Qiuqiu;  Yan, Shike;  Guo, Yu;  Shen, Zheyuan;  Che, Jinxin;  Wu, Yize;  Tong, Lexian;  Dong, Xiaowu;  Yang, Haiyan
收藏  |  浏览/下载：24/0  |  提交时间：2022/12/23
XPO1  Multiple myeloma  MM.1S  N-phenylsulfonamide  Oral administration  
Strongly Tunable Raman Resonance in InSe under Pressure br 期刊论文
JOURNAL OF PHYSICAL CHEMISTRY C, 2022, 卷号: 126
作者:  Huang, Ge;  Zhou, Yan;  Dong, Zuo-Yuan;  Li, Wei-Jian;  Bu, Ke-Jun;  Zhou, Shi;  Wang, Tao;  Lu, Xu-Jie;  Chen, Xiao-Jia
收藏  |  浏览/下载：38/0  |  提交时间：2022/12/23
DIII-D research advancing the physics basis for optimizing the tokamak approach to fusion energy 期刊论文
NUCLEAR FUSION, 2022, 卷号: 62
作者:  Fenstermacher, M. E.;  Abbate, J.;  Abe, S.;  Abrams, T.;  Adams, M.;  Adamson, B.;  Aiba, N.;  Akiyama, T.;  Aleynikov, P.;  Allen, E.;  Allen, S.;  Anand, H.;  Anderson, J.;  Andrew, Y.;  Andrews, T.;  Appelt, D.;  Arbon, R.;  Ashikawa, N.;  Ashourvan, A.;  Aslin, M.;  Asnis, Y.;  Austin, M.;  Ayala, D.;  Bak, J.;  Bandyopadhyay, I;  Banerjee, S.;  Barada, K.;  Bardoczi, L.;  Barr, J.;  Bass, E.;  Battaglia, D.;  Battey, A.;  Baumgartner, W.;  Baylor, L.;  Beckers, J.;  Beidler, M.;  Belli, E.;  Berkery, J.;  Bernard, T.;  Bertelli, N.;  Beurskens, M.;  Bielajew, R.;  Bilgili, S.;  Biswas, B.;  Blondel, S.;  Boedo, J.;  Bogatu, I;  Boivin, R.;  Bolzonella, T.;  Bongard, M.;  Bonnin, X.;  Bonoli, P.;  Bonotto, M.;  Bortolon, A.;  Bose, S.;  Bosviel, N.;  Bouwmans, S.;  Boyer, M.;  Boyes, W.;  Bradley, L.;  Brambila, R.;  Brennan, D.;  Bringuier, S.;  Brodsky, L.;  Brookman, M.;  Brooks, J.;  Brower, D.;  Brown, G.;  Brown, W.;  Burke, M.;  Burrell, K.;  Butler, K.;  Buttery, R.;  Bykov, I;  Byrne, P.;  Cacheris, A.;  Callahan, K.;  Callen, J.;  Campbell, G.;  Candy, J.;  Canik, J.;  Cano-Megias, P.;  Cao, N.;  Carayannopoulos, L.;  Carlstrom, T.;  Carrig, W.;  Carter, T.;  Cary, W.;  Casali, L.;  Cengher, M.;  Paz, G. Cespedes;  Chaban, R.;  Chan, V;  Chapman, B.;  Char, I;  Chattopadhyay, A.;  Chen, R.;  Chen, J.;  Chen, X.;  Chen, X.;  Chen, J.;  Chen, M.;  Chen, J.;  Chen, Z.;  Choi, M.;  Choi, W.;  Choi, G.;  Chousal, L.;  Chrobak, C.;  Chrystal, C.;  Chung, Y.;  Churchill, R.;  Cianciosa, M.;  Clark, J.;  Clement, M.;  Coda, S.;  Cole, A.;  Collins, C.;  Conlin, W.;  Cooper, A.;  Cordell, J.;  Coriton, B.;  Cote, T.;  Cothran, J.;  Creely, A.;  Crocker, N.;  Crowe, C.;  Crowley, B.;  Crowley, T.;  Cruz-Zabala, D.;  Cummings, D.;  Curie, M.;  Curreli, D.;  Dal Molin, A.;  Dannels, B.;  Dautt-Silva, A.;  Davda, K.;  De Tommasi, G.;  De Vries, P.;  Degrandchamp, G.;  Degrassie, J.;  Demers, D.;  Denk, S.;  Depasquale, S.;  Deshazer, E.;  Diallo, A.;  Diem, S.;  Dimits, A.;  Ding, R.;  Ding, S.;  Ding, W.;  Do, T.;  Doane, J.;  Dong, G.;  Donovan, D.;  Drake, J.;  Drews, W.;  Drobny, J.;  Du, X.;  Du, H.;  Duarte, V;  Dudt, D.;  Dunn, C.;  Duran, J.;  Dvorak, A.;  Effenberg, F.;  Eidietis, N.;  Elder, D.;  Eldon, D.;  Ellis, R.;  Elwasif, W.;  Ennis, D.;  Erickson, K.;  Ernst, D.;  Fasciana, M.;  Fedorov, D.;  Feibush, E.;  Ferraro, N.;  Ferreira, J.;  Ferron, J.;  Fimognari, P.;  Finkenthal, D.;  Fitzpatrick, R.;  Fox, P.;  Fox, W.;  Frassinetti, L.;  Frerichs, H.;  Frye, H.;  Fu, Y.;  Gage, K.;  Quiroga, J. Galdon;  Gallo, A.;  Gao, Q.;  Garcia, A.;  Garcia Munoz, M.;  Garnier, D.;  Garofalo, A.;  Gattuso, A.;  Geng, D.;  Gentle, K.;  Ghosh, D.;  Giacomelli, L.;  Gibson, S.;  Gilson, E.;  Giroud, C.;  Glass, F.;  Glasser, A.;  Glibert, D.;  Gohil, P.;  Gomez, R.;  Gomez, S.;  Gong, X.;  Gonzales, E.;  Goodman, A.;  Gorelov, Y.;  Graber, V;  Granetz, R.;  Gray, T.;  Green, D.;  Greenfield, C.;  Greenwald, M.;  Grierson, B.;  Groebner, R.;  Grosnickle, W.;  Groth, M.;  Grunloh, H.;  Gu, S.;  Guo, W.;  Guo, H.;  Gupta, P.;  Guterl, J.;  Guttenfelder, W.;  Guzman, T.;  Haar, S.;  Hager, R.;  Hahn, S.;  Halfmoon, M.;  Hall, T.;  Hallatschek, K.;  Halpern, F.;  Hammett, G.;  Han, H.;  Hansen, E.;  Hansen, C.;  Hansink, M.;  Hanson, J.;  Hanson, M.;  Hao, G.;  Harris, A.;  Harvey, R.;  Haskey, S.;  Hassan, E.;  Hassanein, A.;  Hatch, D.;  Hawryluk, R.;  Hayashi, W.;  Heidbrink, W.;  Herfindal, J.;  Hicok, J.;  Hill, D.;  Hinson, E.;  Holcomb, C.;  Holland, L.;  Holland, C.;  Hollmann, E.;  Hollocombe, J.;  Holm, A.;  Holmes, I;  Holtrop, K.;  Honda, M.;  Hong, R.;  Hood, R.;  Horton, A.;  Horvath, L.;  Hosokawa, M.;  Houshmandyar, S.;  Howard, N.;  Howell, E.;  Hoyt, D.;  Hu, W.;  Hu, Y.;  Hu, Q.;  Huang, J.;  Huang, Y.;  Hughes, J.;  Human, T.;  Humphreys, D.;  Huynh, P.;  Hyatt, A.;  Ibanez, C.;  Ibarra, L.;  Icasas, R.;  Ida, K.;  Igochine, V;  In, Y.;  Inoue, S.;  Isayama, A.;  Izacard, O.;  Izzo, V;  Jackson, A.;  Jacobsen, G.;  Jaervinen, A.;  Jalalvand, A.;  Janhunen, J.;  Jardin, S.;  Jarleblad, H.;  Jeon, Y.;  Ji, H.;  Jian, X.;  Joffrin, E.;  Johansen, A.;  Johnson, C.;  Johnson, T.;  Jones, C.;  Joseph, I;  Jubas, D.;  Junge, B.;  Kalb, W.;  Kalling, R.;  Kamath, C.;  Kang, J.;  Kaplan, D.;  Kaptanoglu, A.;  Kasdorf, S.;  Kates-Harbeck, J.;  Kazantzidis, P.;  Kellman, A.;  Kellman, D.;  Kessel, C.;  Khumthong, K.;  Kim, E.;  Kim, H.;  Kim, J.;  Kim, S.;  Kim, J.;  Kim, H.;  Kim, K.;  Kim, C.;  Kimura, W.;  King, M.;  King, J.;  Kinsey, J.;  Kirk, A.;  Kiyan, B.;  Kleiner, A.;  Klevarova, V;  Knapp, R.;  Knolker, M.;  Ko, W.;  Kobayashi, T.;  Koch, E.;  Kochan, M.;  Koel, B.;  Koepke, M.;  Kohn, A.;  Kolasinski, R.;  Kolemen, E.;  Kostadinova, E.;  Kostuk, M.;  Kramer, G.;  Kriete, D.;  Kripner, L.;  Kubota, S.;  Kulchar, J.;  Kwon, K.;  La Haye, R.;  Laggner, F.;  Lan, H.;  Lantsov, R.;  Lao, L.;  Esquisabel, A. Lasa;  Lasnier, C.;  Lau, C.;  Leard, B.;  Lee, J.;  Lee, R.;  Lee, M.;  Lee, M.;  Lee, Y.;  Lee, C.;  Lee, J.;  Lee, S.;  Lehnen, M.;  Leonard, A.;  Leppink, E.;  Lesher, M.;  Lestz, J.;  Leuer, J.;  Leuthold, N.;  Li, X.;  Li, K.;  Li, E.;  Li, G.;  Li, L.;  Li, Z.;  Li, J.;  Li, Y.;  Lin, Z.;  Lin, D.;  Liu, X.;  Liu, J.;  Liu, Y.;  Liu, T.;  Liu, Y.;  Liu, C.;  Liu, Z.;  Liu, C.;  Liu, D.;  Liu, A.;  Liu, D.;  Loarte-Prieto, A.;  Lodestro, L.;  Logan, N.;  Lohr, J.;  Lombardo, B.;  Lore, J.;  Luan, Q.;  Luce, T.;  Di Cortemiglia, T. Luda;  Luhmann, N.;  Lunsford, R.;  Luo, Z.;  Lvovskiy, A.;  Lyons, B.;  Ma, X.;  Madruga, M.;  Madsen, B.;  Maggi, C.;  Maheshwari, K.;  Mail, A.;  Mailloux, J.;  Maingi, R.;  Major, M.;  Makowski, M.;  Manchanda, R.;  Marini, C.;  Marinoni, A.;  Maris, A.;  Markovic, T.;  Marrelli, L.;  Martin, E.;  Mateja, J.;  Matsunaga, G.;  Maurizio, R.;  Mauzey, P.;  Mauzey, D.;  Mcardle, G.;  Mcclenaghan, J.;  Mccollam, K.;  Mcdevitt, C.;  Mckay, K.;  Mckee, G.;  Mclean, A.;  Mehta, V;  Meier, E.;  Menard, J.;  Meneghini, O.;  Merlo, G.;  Messer, S.;  Meyer, W.;  Michael, C.;  Michoski, C.;  Milne, P.;  Minet, G.;  Misleh, A.;  Mitrishkin, Y.;  Moeller, C.;  Montes, K.;  Morales, M.;  Mordijck, S.;  Moreau, D.;  Morosohk, S.;  Morris, P.;  Morton, L.;  Moser, A.;  Moyer, R.;  Moynihan, C.;  Mrazkova, T.;  Mueller, D.;  Munaretto, S.;  Burgos, J. Munoz;  Murphy, C.;  Murphy, K.;  Muscatello, C.;  Myers, C.;  Nagy, A.;  Nandipati, G.;  Navarro, M.;  Nave, F.;  Navratil, G.;  Nazikian, R.;  Neff, A.;  Neilson, G.;  Neiser, T.;  Neiswanger, W.;  Nelson, D.;  Nelson, A.;  Nespoli, F.;  Nguyen, R.;  Nguyen, L.;  Nguyen, X.;  Nichols, J.;  Nocente, M.;  Nogami, S.;  Noraky, S.;  Norausky, N.;  Nornberg, M.;  Nygren, R.;  Odstrcil, T.;  Ogas, D.;  Ogorman, T.;  Ohdachi, S.;  Ohtani, Y.;  Okabayashi, M.;  Okamoto, M.;  Olavson, L.;  Olofsson, E.;  Omullane, M.;  Oneill, R.;  Orlov, D.;  Orvis, W.;  Osborne, T.;  Pace, D.;  Canal, G. Paganini;  Martinez, A. Pajares;  Palacios, L.;  Pan, C.;  Pan, Q.;  Pandit, R.;  Pandya, M.;  Pankin, A.;  Park, Y.;  Park, J.;  Park, J.;  Parker, S.;  Parks, P.;  Parsons, M.;  Patel, B.;  Pawley, C.;  Paz-Soldan, C.;  Peebles, W.;  Pelton, S.;  Perillo, R.;  Petty, C.;  Peysson, Y.;  Pierce, D.;  Pigarov, A.;  Pigatto, L.;  Piglowski, D.;  Pinches, S.;  Pinsker, R.;  Piovesan, P.;  Piper, N.;  Pironti, A.;  Pitts, R.;  Pizzo, J.;  Plank, U.;  Podesta, M.;  Poli, E.;  Poli, F.;  Ponce, D.;  Popovic, Z.;  Porkolab, M.;  Porter, G.;  Powers, C.;  Powers, S.;  Prater, R.;  Pratt, Q.;  Pusztai, I;  Qian, J.;  Qin, X.;  Ra, O.;  Rafiq, T.;  Raines, T.;  Raman, R.;  Rauch, J.;  Raymond, A.;  Rea, C.;  Reich, M.;  Reiman, A.;  Reinhold, S.;  Reinke, M.;  Reksoatmodjo, R.;  Ren, Q.;  Ren, Y.;  Ren, J.;  Rensink, M.;  Renteria, J.;  Rhodes, T.;  Rice, J.;  Roberts, R.;  Robinson, J.;  Fernandez, P. Rodriguez;  Rognlien, T.;  Rosenthal, A.;  Rosiello, S.;  Rost, J.;  Roveto, J.;  Rowan, W.;  Rozenblat, R.;  Ruane, J.;  Rudakov, D.;  Ruiz, J. 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收藏  |  浏览/下载：39/0  |  提交时间：2022/12/23
DIII-D  tokamak  fusion energy  plasma physics  core-edge integration  
Sugemalimab versus placebo after concurrent or sequential chemoradiotherapy in patients with locally advanced, unresectable, stage III non-small-cell lung cancer in China (GEMSTONE-301): interim results of a randomised, double-blind, multicentre, phase 3 trial 期刊论文
LANCET ONCOLOGY, 2022, 卷号: 23
作者:  Zhou, Qing;  Chen, Ming;  Jiang, Ou;  Pan, Yi;  Hu, Desheng;  Lin, Qin;  Wu, Gang;  Cui, Jiuwei;  Chang, Jianhua;  Cheng, Yufeng;  Huang, Cheng;  Liu, Anwen;  Yang, Nong;  Gong, Youling;  Zhu, Chuan;  Ma, Zhiyong;  Fang, Jian;  Chen, Gongyan;  Zhao, Jun;  Shi, Anhui;  Lin, Yingcheng;  Li, Guanghui;  Liu, Yunpeng;  Wang, Dong;  Wu, Rong;  Xu, Xinhua;  Shi, Jianhua;  Liu, Zhihua;  Cui, Na;  Wang, Jingru;  Wang, Qiang;  Zhang, Ran;  Yang, Jason;  Wu, Yi-Long
收藏  |  浏览/下载：71/0  |  提交时间：2022/03/21
Defect evolution in tungsten exposed to helium plasma and deuterium plasmas studied by slow positron beam 期刊论文
NUCLEAR MATERIALS AND ENERGY, 2021, 卷号: 29
作者:  Lyu, Yi-Ming;  Xu, Yu-Ping;  Li, Xiao-Chun;  Shen, Xin;  Wu, Bo-Yu;  Yip, Chi-Shung;  Gao, Xiang;  Lin, Xiao-Dong;  Yang, Zhong-Shi;  Cao, Xing-Zhong;  Zhou, Hai-Shan;  Luo, Guang-Nan
收藏  |  浏览/下载：97/0  |  提交时间：2022/01/10
Tungsten  Helium  Deuterium  Defects  EAST