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Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop 期刊论文
NUTRIENTS, 2022, 卷号: 14
Authors:  Tang, Hengfang;  Zheng, Zhiming;  Wang, Han;  Wang, Li;  Zhao, Genhai;  Wang, Peng
Favorite  |  View/Download:7/0  |  Submit date:2022/05/16
vitamin K2  apoptosis  ROS  mitochondrial dysfunction  mitophagy  mitochondrial biogenesis  mitochondrial quality-control loop  PINK1  Parkin signaling pathway  
Engineering microbial consortia of Elizabethkingia meningoseptica and Escherichia coli strains for the biosynthesis of vitamin K2 期刊论文
Microbial Cell Factories, 2022, 卷号: 21
Authors:  Yang,Qiang;  Zheng,Zhiming;  Zhao,Genhai;  Wang,Li;  Wang,Han;  Ding,XiuMin;  Jiang,Chunxu;  Li,Chu;  Ma,Guoliang;  Wang,Peng
Favorite  |  View/Download:30/0  |  Submit date:2022/05/16
Vitamin K2  Microbial consortia  Metabolic engineering  Elizabethkingia meningoseptica  
Cloning and functional characterization of the geranylgeranyl diphosphate synthase(GGPPS)from Elizabethkingia meningoseptica sp.F2 期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2022, 卷号: 189
Authors:  Yang, Qiang;  Zheng, Zhiming;  Zhao, Genhai;  Wang, Li;  Wang, Han;  Ni, Wenfeng;  Sun, Xiaowen;  Zhang, Mengxue;  Tang, Hengfang;  Wang, Peng
Favorite  |  View/Download:19/0  |  Submit date:2021/11/29
Elizabethkingia meningoseptica  Geranylgeranyl diphosphate synthase  Soluble expression  MK-4  
A study of hydrophobins-modified menaquinone-7 on osteoblastic cells differentiation 期刊论文
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2021
Authors:  Tang, Hengfang;  Zhu, Zhu;  Zheng, Zhiming;  Wang, Han;  Li, Chu;  Wang, Li;  Zhao, Genhai;  Wang, Peng
Favorite  |  View/Download:8/0  |  Submit date:2021/03/15
Menaquinone-7  Hydrophobins  Alkaline phosphatase  Osteocalcin  OPG  RANKL  Mitochondria  
Synthesis of the carboxymethyl cellulose magnetic nanoparticles for efficient immobilization of prenyltransferase NovQ 期刊论文
CARBOHYDRATE POLYMERS, 2020, 卷号: 235
Authors:  Ni, Wenfeng;  Zheng, Zhiming;  Liu, Hui;  Wang, Peng;  Wang, Li;  Wang, Han;  Sun, Xiaowen;  Yang, Qiang;  Tang, Hengfang;  Zhao, Genhai
Favorite  |  View/Download:21/0  |  Submit date:2020/11/26
Carboxymethyl cellulose  Magnetic nanoparticles  Prenyltransferase NovQ  Immobilization  Prenylated activity  
Combining mutagenesis on Glu281 of prenyltransferase NovQ and metabolic engineering strategies for the increased prenylated activity towards menadione 期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2020
Authors:  Ni, Wenfeng;  Zheng, Zhiming;  Liu, Hui;  Wang, Peng;  Wang, Han;  Sun, Xiaowen;  Yang, Qiang;  Fang, Zhiwei;  Tang, Hengfang;  Zhao, Genhai
Favorite  |  View/Download:178/0  |  Submit date:2020/11/26
Prenyltransferase NovQ  Menadione hydroquinol  Site-directed mutagenesis  Mevalonate pathway  Metabolic engineering  
Construction of a novel MK-4 biosynthetic pathway in Pichia pastoris through heterologous expression of HsUBIAD1 期刊论文
Microbial Cell Factories, 2019, 卷号: 18
Authors:  Sun,Xiaowen;  Liu,Hui;  Wang,Peng;  wang,Li;  Ni,Wenfeng;  Yang,Qiang;  Wang,Han;  Tang,Hengfang;  Zhao,Genhai;  Zheng,Zhiming
Favorite  |  View/Download:13/0  |  Submit date:2020/10/21
Pichia pastoris  Aromatic prenyltransferase  HsUBIAD1  Geranylgeranyl diphosphate synthase  Menaquinone  
Effects of a combined processing technology involving ultrasound and surfactant on the metabolic synthesis of vitamin K-2 by Flavobacterium sp. M1-14 期刊论文
CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION, 2019, 卷号: 135, 期号: 无, 页码: 227-235
Authors:  Fang, Xue;  Yang, Qiang;  Liu, Hui;  Wang, Peng;  Wang, Li;  Zheng, Zhiming;  Zhao, Genhai
View  |  Adobe PDF(1564Kb)  |  Favorite  |  View/Download:69/32  |  Submit date:2020/05/21
Ultrasound  Surfactant  Flow cytometry  Transmission electron microscopy  Vitamin K-2  
Macro-morphological characterization and kinetics of Mortierella alpina colonies during batch cultivation 期刊论文
PLOS ONE, 2018, 卷号: 13, 期号: 8, 页码: 11
Authors:  Fang, Xue;  Zhao, Genhai;  Dai, Jun;  Liu, Hui;  Wang, Peng;  Wang, Li;  Song, Junying;  Zheng, Zhiming
Favorite  |  View/Download:12/0  |  Submit date:2019/11/11
Morphological regulation of Aspergillus niger to improve citric acid production by chsC gene silencing 期刊论文
BIOPROCESS AND BIOSYSTEMS ENGINEERING, 2018, 卷号: 41, 期号: 7, 页码: 1029-1038
Authors:  Sun, Xiaowen;  Wu, Hefang;  Zhao, Genhai;  Li, Zhemin;  Wu, Xihua;  Liu, Hui;  Zheng, Zhiming
Favorite  |  View/Download:412/0  |  Submit date:2019/11/11
Aspergillus niger  Morphology  Citric acid  Chitin synthase  RNA interference